Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
Add to Favorite Get Latest Update

Action Analysis of Rg2、Rf on calcium channel

Zhang Wenjie,Liu Wei,Zhan Shu,et al(Department of Physiology; Central Labolaboratory of Physiology )  
The influence of panaxatrio1 saponin monomers Rg2、Rf 60 μmol·L-1 on single Calci-um channel activity from cultured neonatal Wistar rat myocardiocyte was observed using the cell-at-tached configuration of patch clamp technique,and compared with that of calcium channel blocker ver-apamil 79 μmol·L-1 and calcium channel activator BAY K 8644 5μmol·L-1. The inhibiting effectsof Rg2 on the three-type calcium channels were observed. The mechanism was that Rg2 shortented theopen time ,decreased the open一state probability, lengthened the close time of calcium channels,with-out influencing the amplitude of the ionic current flowing through the opening calcium channel;Rf hadno these actions.
【CateGory Index】: Q463
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 3 Hits
1 SUN Wen juan1, LIU Jie2, LU Yi wei2, TIAN Jian min3, LI Long yun3 (1. Department of Pharmacology, Chongqing University of Medical Sciences, Chongqing 400016, China; 2. Preclinical Medical College, Jilin University, Changchun, Jilin 130021. China; 3. Jilin Academy of TCM. Jilin 130021. China);Effect of ginsenoside Rg_2 on cardiac hemodynamics of anesthetized open chest dog[J];中成药;2004-10
2 XU Zhi-xin,LUO Rong-jing,GUAN Li;Research Review of Chinese Herbs Acting on Calcium Channels[J];中国中医基础医学杂志;2003-11
3 LIU Jie 1, SUN Wen juan 1, L U ¨ Wen wei 1, YE Jin mei 2, LI Long yun 2 (1 Preclinical Medical College, Jilin University, Changchun Jilin 130021, China; 2 Jilin Academy of TCM, Changchun Jilin 130021, China);Comparison of cardiotonic and toxic effects between ginsenoside Rg_2 and strophanthin K[J];中草药;2001-09
Chinese Journal Full-text Database 1 Hits
1 Jiang Yan, Zhong Guogan, Shao Chunjie and Yue Gang (Norman Bethune University of Medical Sciences, Changchun 130021);Ca~(2+) Channel Blocking Effect of Panaxadiol Saponins and Panaxatriol Saponins on Cultured Cardiac Cells[J];中国中药杂志;1992-03
Chinese Journal Full-text Database 10 Hits
1 SUN Fa-lin;LI Jing-qin;ZHANG Jin-ping;Dept.of Nephrology,No.401 Hospital,Chinese PLA;;Combined treatment of crawling creatinine following renal transplantation[J];实用医药杂志;2015-04
2 AN Hui,MIAO Can-ming,LING Kai-xuan Zhongshan hospital of TCM,Guangdong Province ( Zhongshan 528400);Effect of Shenmaifulv Decoction on Rat Arrhythmia induced by Aconitine and Calcium Chloride[J];中国中医急症;2010-09
3 LI Qian,MA Hui-jie,GUAN Yue,GAO Lu,ZHANG Yi(Dept of Physiology,Hebei Medical University,Shijiazhuang 050017,China);Influences of ginsenoside Rg1 on spontaneous contraction of small intestine smooth muscle of rabbits in vitro[J];中国药理学通报;2009-10
4 AN Hui,MIAO Can-ming,LIN Kai-xuan(Zhongshan Hospital of TCM,Zhongshan 528400,Guangdong,China);The Effect of Pulse-Engendering Palpitation-Stabilizing Decoction on Patients With Tacho-Arrhythmia Cordis[J];中华中医药学刊;2009-05
5 WANG Hong-Yi, YU Bo-Yang,YU Biao, HUI Yong-Zheng School of Chinese traditional pharmacy, China Pharmaceutical University, Nanjing, 210009 P. R. China; Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , P. R. China.;Comparison of Intracellular Ca~(2+) Patterns Affected by Steriod Saponin Trilliuo, Lc253 and Lc239 in Cultured Cardiomyocytes Revealed by Confocal Microscopy[J];中国天然药物;2003-01
6 Wang Jingxia , Deng Wenwel, Qi Yaling, et al, Dpartment of Histology and Embryology, College of Basic Medicine, Jiamusi University, Jiamusi 154002;Protective effects of Salvia miltiorrhiza and ligustrazine on the damage of rat kidney induced by gentamicin[J];中国局解手术学杂志;2002-03
7 Li Huifang, et al (Pediatric Department, The First Hospital,Beijing Medical University);REVERSAL OF MULTIDRUG RESISTANCE BY GINSENOSIDER Rb1 IN THE HUMAN RESISTANT TUMOR CELLS[J];中国小儿血液;1999-04
8 DuZhaopeng,DuXuehai,LiuJie,etal.DepartmentofNephrology,China-JapanFriendshipHos-pital,Beijing100029;Roleofreactiveoxygenmetabolites(ROM)ingentamicinnephrotoxicityinratsandtheprotectiveefectofROMscavengers[J];中华肾脏病杂志;1996-02
9 Zhan Shu Zhang Wen-jie Liu Wei* Dept.of Physiology,Norman Bethune University of Medical Sciences,Changchun(130021) *Physiologic Central Laboratory.Norman Bethune University of Medical Sciences;Study of Ginseng Monomer Rg_2 on Calcium Channel and Electronic Spin Resonance Spectra[J];中国中西医结合杂志;1995-S1
10 Zhang Wenjie,Liu Wei,Zhan Shu,et al(Department of Physiology; Central Labolaboratory of Physiology );Action Analysis of Rg2、Rf on calcium channel[J];白求恩医科大学学报;1995-05
Chinese Journal Full-text Database 10 Hits
1 SUN Wen-Juan,LIU Jie ,LU Wen-Wei,YE Jin-Mei ,LI Long-Yun (Dept of Pharmacology ,Chongqing University of Medical Sciences, Chongqing 400016) Preclinical Medical college, Jilin University, Changchun 130021 Jilin Academy of TCM, Jilin 130021;Effects of ginsenoside Rg_2 on heart failure induced by pentobarbital sodium in dogs[J];中国药理学通报;2003-06
2 LIU Jie 1, SUN Wen juan 1, L U ¨ Wen wei 1, YE Jin mei 2, LI Long yun 2 (1 Preclinical Medical College, Jilin University, Changchun Jilin 130021, China; 2 Jilin Academy of TCM, Changchun Jilin 130021, China);Comparison of cardiotonic and toxic effects between ginsenoside Rg_2 and strophanthin K[J];中草药;2001-09
3 DU Zhi min,QIU Xiao hong,LI Bao xin,ZHANG Bo,HUANG Li jun,LIU Yan,WANG Zhen (The Second Hospital of Harbin Medical University,Harbin 150086,China);Protect effect of Guanxin capsule on myocardial ischemia in rats[J];中国药学杂志;2000-10
4 YANG Li Zhen,ZHANG Yi 1,LI Jin Xi,ZHU Yi Chun 2,ZHANG Zhi Xiong 3,LI Yan,ZHOU Zhao Nian 1 (Cardiological Department of Affiliated Yueyang Hospital, Shanghai University of Chinese Traditional Medicine, Shanghai 200437);Effects of BN-52021 on AP and L-type calcium channel in guinea pig's ventricular myocytes[J];中国药理学通报;2000-02
5 WANG Zhong-Feng, et al (Department of Biochemical Pharmacology);Effects of tetrandrine on calcium channels in rat cortical neurons[J];重庆医科大学学报;2000-01
6 Department of Pharmacology, Tongji University of Medical Sciences (Wuhan 430030) Wang Jialing, Nong Yi, Yao Weixing and Jiang Mingxing;Effects of Liensinine on Action Potentials and I_(Na) , I_(Ca-L) in Guinea Pig Ventricular Myocytes[J];中草药;2000-03
7 WANG Zhong Feng 1, XUE Chun Sheng 1, ZHOU Qi Xin 1, WAN Zi Bing 2, LUO Quan Sheng 2 (1. Department of Pharmacology, Chongqing University of Medical Sciences, Chongqing 400046, China; 2. Department of Physiology, The Third Military Medical U;Effect of tetrandrine on the functional changes in calcium channels induced by anoxia in cerebral cortical neurons acutely isolated from rats[J];中国药理学与毒理学杂志;2000-01
8 Lu Yueming,Chen Long,Cai Baochang,Ma Cheng,Shi Zhiyang,Li Xian (Nanjing TCM University,Nanjing 210029);SINGLE CHANNEL ANALYSIS AND ELECTRON MICROGRAPH STUDY ON MYOCARDIAL EFFECTS OF ISOBRUCINE[J];安徽中医学院学报;1999-06
9 ZhangBin (ICU ,HospitalofChineseTraditionalMedicineofGuangdongProvince ,FuShan 5 2 80 0 0 ) JinShiao(DepatmentofAnesthesiology,theAffiliatedHospital,TongjiMedicalUniversity ,Wuhan 4 30 0 30 ) KuangXian(ICU ,theFirstAffiliatedHospitalofKunmingMedicalColl;Effects of Rg_1 on Calcium Channel of Guinea Pig Ventricular Myocytes[J];中国中药杂志;1999-10
10 SHAN Hong Li,XU Chang Qing,LIU Feng Zhi,LI Yu Rong, YANG Bao Feng,XU Hong Yuan,LOU Yan Ping (Dept of Pathophysiology,Harbin Medical University,Harbin 150086);Effects of safflower yellow pigment on action potential duration and calcium current in single guinea pig ventricular myocytes[J];中国药理学通报;1999-04
【Secondary References】
Chinese Journal Full-text Database 9 Hits
1 ZHOU Bai-song;YANG Na;LI Ya-meng;WANG Ya-ru;LIU Jin-ping;ZHANG Zhi-dong;LI Ping-ya;Pharmacy College of Jilin University;Kangmei Xinkaihe (jilin) Pharmaceutical Company Limited;;Advances in Research of Biological Activities of Ginsenoside Rg2[J];特产研究;2017-02
2 WU Yi-hang;WU Yan;LIU Xin-yu;LIU Jie;WANG Qiu-jing;LIU Fen;LV Wen-wei;DI Lin;Tongji Medical College,Huazhong University of Science and Technology;Chinese Medicine Science Academy of Jilin Province;Jilin University;;Effect of Ginseng Sini Granules on myocardial blood flow in Beagle Dogs with heart failure[J];人参研究;2017-02
3 YANG Xiu-wei;LI Ke-ke;ZHOU Qi-le;State Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences,Peking University;;20(S)-Ginsenoside-Rf_2, a novel triterpenoid saponin from stems and leaves of Panax ginseng[J];中草药;2015-21
4 JIN Ying-hua;LI Long-yun;The First Affi liated Hospital of Guangdong Pharmaceutical University;Jilin Academy of Chinese medicine science;;Effects of Ginsenoside Rg2 on the Heart Rate and Blood Pressure in Dogs Under Super Effi cacy Measurement[J];深圳中西医结合杂志;2015-11
5 LU Junguang;HE Mingfeng;ZHANG Yingjian;Foshan Hospital of Traditional Chinese Medicine;;Influence of Shenfu injection on partial pressure of end-tidal carbon dioxide in cardiopulmonary resuscitation[J];现代中西医结合杂志;2015-09
6 Chen Huade;Zheng Yanqing;Wang Yan;Zhao Xingmei;Zhejiang Chinese Medical University;;Effects of Point Injection with Different Reinforcing and Reducing Manipulation to Cardiac Function of Heart-qi Deficiency Syndrome Model in Rats[J];浙江中医药大学学报;2014-01
7 WANG Li LV Xiao-jun WANG Li-yan ZHANG Jing(College of Traditional Chinese Medicinal Materials,Jilin Agricultural University,Changchun 130118,China);The pharmacology proress of Panax ginseng C.A. Meyer on experimental heart failure[J];人参研究;2012-02
8 LI Fan-zhu1 JIN Tie1 CUI Fu-shun1 LV Long-shi1 RYU Gi-hyung2(1.Agricultural College of Yanbian University,Longjing,Jilin 133400,China;2.Department of Food Science and Technology,Kongju National University,Yesan,Chongnam 340-804,Korea);Study on expansion properties of extruded giseng by twin-screw extruder[J];食品与机械;2010-03
9 QIU Guo-song1,WANG Tian-shan2,ZHAO Shu-min2(Panagin Pharmaceuticals Inc.,Richmond,BC,Canada,V6X 1Z7);Dammarane Saponins Effect on Exercise Endurance and Fatigue[J];体育科研;2009-03
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved