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《JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE》 1996-05
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Elcectro-acupuncture analgesia produced by septal area inhibiting habenula activity with GABAA

Pan Yuzhne;Huang Min;Wu Jianqun et al(Department of physiology)  
The unit firings from habenula were recorded by multi-microelectrodes and the pain threshold was measured in rats.GABA could entirely inhibit the spontaneous firings of habenula.The spontaneous firings of habenula could be inhibited by the stimuli of septal area but bicuculline could weaken this effect.Microinjecting GABA into habenulae increased the pain threshold significantly,but bicuculline apparently reduced the pain threshold and antagonized the effect of acupuncture analgesia.These results suggested that the septal area inhibited the habenula activity to produce the electro-acupuncture analgesia with GABAA.
【CateGory Index】: R454.1
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