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《JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE》 1997-02
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Histochemical and electromicroscopic observation on effects of low dose chlorides of lanthanum and ytterbium on rat liver

Nie Yuxiu,Cui Yanan ,Huang Kexin,et al (The School of Basic Medical Sciences; Third Clinical Collgeg)  
To study the effects of the low dose of chlorides of lanthanum and ytterbium on the rat liver structure and hepatocyte glycogen,the methods of histochemistry PAS reaction,electromicroscopy and image analysis system were used after the rats were given LaCl 3 and YbCl 3 by three ways of intraperitoneal injection,peroral and tail vein injection every other day for four weeks (0.05 mg/kg bw×12) respectively.The results showed that in the experimental groups,the general structure of liver did not change,mitotic hepatocyte and the mast cell in the hepatic area increased,the ultrastructure of hepatocyte also did not change,only the amount of the hepatocyte glycogen increased and the grey level value of glycogen in liver cell decreased.
【Fund】: 国家自然科学基金资助项目
【CateGory Index】: O614.1
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