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《JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE》 1998-03
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Expression of TGFβ·VEGF and PCNA on the gut of rats withdifferent embryonic days and its biological significance

Li Haochuan1,Zhu Guibin1,Li Guibo2,Zhao Haijun1,Li Yulin1(1 Dept.of Pathology,NBUMS; 2 Changchun Senior Medical Training School)  
Objective:In order to study modulating mechanism of different cellular factors in genesis and perenchymal cell differentiation of gut.Methods:The expression of TGFβ,VEGF and PCNA on the gut of rats with different embryonic days were investigated by the immunohistochemical and morphological analystic methods.Results:①TGFβ,VEGF and PCNA had positive expression on the gut;②TGFβ expressed highly on the epithelial and interstitial of gut in E13;③PCNA expressed highly around E18;④VEGF expressed highly on the interstitial around E13E14,then expressed highly on the epithelial in the E18.Conclusion:TGFβ and VEGF could play an important role in the regulation of cell proliferation and differentiation.
【CateGory Index】: R361,
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