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《Journal of Bethune Military Medical College》 2004-01
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Effect of Injecting 5-HT,Substance P into NRM on the Rabbits' Gastric Motility and Gastric Myoelectric Activity

CHEN Xiangmei ,LIU Bin,LIU Zhimin. Branch of Harbin Medical University,Jixi 158100,China  
Objective To investigate the effect on both the gastric motility and gastric myoelectrical activity after injecting the 5 HT,Substance P and so on into nucleus raphe magnus(NRM). Methods Hall's effect principle was adopted to record the changes of gastric motility and gastric myoelectrical slow wave.The changes of stomach were observed after injecting 5 HT,CYP,SP,DADTL,Morphine and NE into NRM. Results ①The frequency and wave amplitude of gastric motility and gastric myoeletrical slow wave could be partly repressed by NRM injection of 5 HT and SP.②The gastric motility and gastric myoelectrical slow wave could be increased after injecting CYP,DADTL into NRM.③NRM injection of Morphine and NE have no effect on gastric motility and gastric myoelectrical slow wave. Conclusion The 5 HT and SP in NRM is involved in the regulation of stomach and the 5 HT in NRM is mediated by 5 HT 2 receptors,but the Morphine and the NE in NRM isn't involved in the regulation.
【CateGory Index】: R338
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【Co-citations】
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