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《Journal of Beijing Normal University(Natural Science)》 2008-03
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FUZHENG-YILIU DECOCTION ON TUMOR CELL TELOMEREASE AND BLOOD VISCOSITY IN TUMOR-BEARING MICE

ZHANG Yuhong1) CHAI Weizhong2) ZHAO Jianxiong3)(1)The Hospital of Beijing Normal University,100875,Beijing,China;2)Public Health School of Peking University,100083,Beijing,China;3)Institute of Traditional Chinese and Western Integrated Medicine,Lanzhou University Medical College,730000,Lanzhou,China)  
Kunming mice was inoculated with tumor cell S180,and drugs administered by gastrogavage.Tumor cell telomerease activity and blood viscosity was measured.Compared with control,telomerease activity was reduced significantly by Fuzheng-Yiliu Decotion(P0.001).In addition,tumor-bearing mice had high blood viscosity.After Fuzheng-Yiliu Decoction blood viscosity decreased significantly(P0.001).Fuzheng-Yiliu Decoction can inhibit telomerease activity and decrease blood viscosity,which may explain tumor cells become resistant to Fuzheng-Yiliu Decoction.
【CateGory Index】: R73-3
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【References】
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4 HU Guang-sheng,SHI Wei,LIAO Ai-jun,et al(Department of Digestion,the First Affiliated Hospital of Nanhua University,Hengyang,Hunan 421001,China);The Effect of Curcumin on Expression of P300,P53,c-myc and Acetyl Histone H3,H4 in the Gastric Cancer Cell[J];Journal of Nanhua University(Medical Edition);2005-04
5 Ying Mei Su Xiulan Qu Yunzhi Eer Dun 1 The Central Laboratory in the Affiliated Hospital of Inner Mongolia Medical College,Hohehot,010050,China; 2 Beijing Zhengda Oasis Pharmacology and Technology,Com.Ltd.,Beijing 010000,China; 3 The Police's General Hospital of Inner Mogolia,Hohehot 010050,China;Inhibition of ursolic acid on S-180 sarcoma in mice and its mechanism[J];Chinese Journal of Anatomy;2007-05
6 ZHANG Chun Yang 1), GONG Yi Xuan 2), MA Hui 1)**,AN Cheng Cai 2), CHEN Die Yan 1)( 1)Molecular and Nano Sciences Laboratory, Department of Physics, Tsinghua University, Beijing 100084, China; 2)National Laboratory of Protein Eng;Studying the Effect of Trichosanthin on Choriocarcinoma Cells with both Two-photon and Confocal Laser Scanning Microscopy[J];Progress In Biochemistry and Biophysics;2001-05
7 Zhang Shaohua Gao Shangfeng Hao Zhiming Department of Gynecology and Obstertrics,Affiliated Hospital of Xian Medical College(Xi'an 710077);The effcet of arsenic trioxide on the telomerase activity expression in human ovarian cancer cell line SKOV_3[J];Shaanxi Medical Journal;2008-08
8 ZHANG Hong-jun,TANG Xiao-yun,JU Bao-ling,SONG Bao-huiDepartment of Pathogenic Biology,Mudanjiang Medical College,Mudanjiang 157011,China;Effect of yupingfengsan on the growth of tumor and immunological function in tumor-bearing mice[J];Chinese Journal of Cellular and Molecular Immunology;2008-07
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