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《Journal of Capital Institute of Physical Education》 2011-03
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Effects of Different Hypoxia Training Methods on Brain cAMP and Free Radical Metabolism of Rats

WANG Rengang1,LIN Wentao1,LIANG Wei2,WENG Xiquan1 1.Science Experimental Center,Guangzhou Sport University,Guangzhou 510500,China;2.Jinan University,Guangzhou 510632,China.  
Objective:To substantiate the effects of different hypoxia training methods on brain cAMP and free radical of rats.Methods:37 male Sprague-Drawly(SD) rats(180~220g body weight) were randomly divided into 4 groups:training at low altitude(LL),living high-training high(HH),living high and training low(HL),living low and training high(LH).In the hypoxic environment the oxygen content was 15.4%.The rats were trained on a treadmill using a progressive protocol that plateau at 25m/min in normal environment and at 20m/min in hypoxic environment for 1hr/day,6days/week for a total of four weeks.Results:The level of cAMP of HL and LH group were higher than HH group.but both were no significant difference(P0.05).The level of SOD of HL and LH groups were significantly higher than HH and LL groups,the level of MDA of HH,LH and HL groups were lower than LL group.Conclusion:the hypoxia training methods of HH,HL and LH can increase the content of brain anti-oxidation of rats,which are benefit to maintain the brain function,and LH and HL are better than HH,which can maintain the content of brain cAMP of rats.
【CateGory Index】: G804.7
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