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《Journal of Baotou Medical College》 2002-03
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Changes of SOD,MDA in Several Cardiovascular Diseases

Zheng Yuyun, Zhang Zhao, Guo Xiaohua , et al (ICU, The first affiliated hospital of Baotou Medical College, Baotou 014010,China)  
Objective: To observe the changes of superoxide dismutase (SOD) and malonyldialdehyde(MAD) in several cardiovascular diseases. Methods:The levels of SOD and MDA of 156 cases with cardiovascular diseases were measured, (41 of them were cor pulmonale ; 77 were coronary heart disease; 38 were hypertension). Results: Compared with the control group, the level of SOD dropped by 38.78% in cardiovascular diseases group (P0.01), that of MDA was lowered by 140.58% (P0.01), SOD/MDA was decreased by 73.30% (P0.01) . Conclusion: The free radial metabolism was disordered in cor pulmonale, coronary heart disease and hypertension. It is saggestd that the free radical-induced lipid peroxidation may contribate to the incidence and the development of these diseases
【CateGory Index】: R54
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