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Advancement of Epigenetic Modifications Regulate Influences Transgenic and the early Development of Cloned Embryo

ZHANG Jin-rong1,MA Jing-jing(1.Xianyang Qindu district rual nenerge office,Xianyang,Shananxi,712001,China;2.Collage of Animal Medicine,Northwest A & F University,Yangling,Shananxi,712100,China)  
Epigenetic modifications plays an important role in gene expression and the early development of cloned embryo.From four aspects including DNA methylation,histone acetylation,chromatin remodeling and non-coding RNAs,this article discribed the mechanism of epigenetic modifications and its effects on transgene and the early development of cloned embryo.The article has great instructional significants for researching epigenetic modifications.
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