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《China Journal of Traditional Chinese Medicine and Pharmacy》 2003-04
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Effect of Pueraria Flavone on Liver Lipid Metabolism in Ovariectomized Rats

Jin Huan et al ( Beijing University of TCM )  
Objective: To study the action of Pueraria Flavone on liver lipid metabolism in ovariectomized rats. Methods: Adult female ovariectomized model rats were used in this experiment. One week after operation 40 ovariectomized rats were given Pueraria Flavone by oral administration for 5 weeks respectively (10g/kg). The effect of drug on weight, the amount of abdominal fat, wet weight of uterus, liver total cholesterol and triglycerides were observed after the rats were killed. Results: Rats in the model group gain weight markedly and fat piling up in the abdomen and liver triglycerides and cholesterol increasing and uterus atrophy ovariectomy six weeks later. The above-noted indices were relieved in different degree after being taken Pueraria Flavone. Conclusion: Pueraria Flavone has some estrogen-like action and may be helpful to prevent and treat menopause syndrome.
【Fund】: 国家自然科学基金;; 北京市自然科学基金资助课题
【CateGory Index】: R285.5
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