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《China Journal of Traditional Chinese Medicine and Pharmacy》 2003-07
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Pharmacodynamic and Toxicologic Research on Nao Mai Kang Capsule

Zou Jieming et al (Guilin Sanjin Pharmaceutical Com. Ltd. )  
Objective: To observe the pharmacologic action of Nao Mai Kang Capsule. Method: To do pharmacodynamic and toxicologic experiments according to the reference literature. Result: Nao Mai Kang Capsule can obviously lessen the neural behavior disorders, reduce the area of cerebral infarction, and lower MDA content in plasma; it can also obviously decrease the pathologic changes of cerebral ischemia in model rat, lower the permeability of the cerebral capillaries, decrease the water content of the brain tissues, and increase the cerebrovascular blood flow volume of a dog; and it can significantly inhibit the coagulation of platelet aggregation and the thrombosis of cerebral ischemia rat, and lower the plasma lipid. The maximal tolerance dose is amounts to 600 times of the therapeutic dose. And the long-term toxicity-test didn't show obvious toxic reaction. Conclusion: Nao Mai Kang Capsule has a preventive effect to ishcemic cerebral vascular diseases, and a therapeutic effect to stroke cases in acute stage. It has no toxic reaction and side effects.
【CateGory Index】: R285
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