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《China Journal of Traditional Chinese Medicine and Pharmacy》 2003-07
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Pharmacodynamic and Toxicologic Research on Nao Mai Kang Capsule

Zou Jieming et al (Guilin Sanjin Pharmaceutical Com. Ltd. )  
Objective: To observe the pharmacologic action of Nao Mai Kang Capsule. Method: To do pharmacodynamic and toxicologic experiments according to the reference literature. Result: Nao Mai Kang Capsule can obviously lessen the neural behavior disorders, reduce the area of cerebral infarction, and lower MDA content in plasma; it can also obviously decrease the pathologic changes of cerebral ischemia in model rat, lower the permeability of the cerebral capillaries, decrease the water content of the brain tissues, and increase the cerebrovascular blood flow volume of a dog; and it can significantly inhibit the coagulation of platelet aggregation and the thrombosis of cerebral ischemia rat, and lower the plasma lipid. The maximal tolerance dose is amounts to 600 times of the therapeutic dose. And the long-term toxicity-test didn't show obvious toxic reaction. Conclusion: Nao Mai Kang Capsule has a preventive effect to ishcemic cerebral vascular diseases, and a therapeutic effect to stroke cases in acute stage. It has no toxic reaction and side effects.
【CateGory Index】: R285
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Chinese Journal Full-text Database 3 Hits
1 Dong-Liang Jiao1, Xiu-Shi Ni2 1Nanjing University of Traditional Chinese Medicine, Nanjing 210029, China; 2Department of Neurology, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China;Animal Model of Transient Ischemic Attacks[J];Cerebrovascular Diseases Foreign Medical Sciences;2005-10
2 XIE Hai-ying,WAN Qi-rong,ZHENG Cheng-hong,et al.Department of Endocrinology,the First Hospital of Wuhan City,Wuhan 430022,China;Effects of Naomaitai Capsules on Prophase Diabetic Foot[J];Chinese General Practice;2008-16
3 ;脑脉泰胶囊对血管性痴呆患者认知功能障碍的康复作用[J];China Medical Herald;2006-29
Chinese Journal Full-text Database 5 Hits
1 Niu Guozhong,Zhao Yu Department of Neurology,Ruijn Hospital,Shanghai Second Medical University,Shanghai;A Model of Local Cerebral Infarction in Rats Using Transcranial Occlusion of the Middle Cerebral Artery[J];Acta Universitatis Medicinalis Secondae Shanghai;1990-02
3 Liu Jia-Liu, Cao Xu-Mao, et al Department of Pathology, Guiyang Medical College and Guizhou Geriatrics Institute, Guiyang;Pathological changes and MDA content of the rat brain in the early stage of middle cerebral artery occlusion[J];Chinese Journal of Pathophysiology;1991-05
4 Lu Guocai.et al.(Second Military Medical Univ.,Shanghai 200433);The Effect of Xing Nao Ying on Cerebral Circulation of Dogs[J];TRADITIONAL CHINESE DRUG RESEARCH & CLINICAL PHARMACOLOGY;1996-01
5 Chen Lifeng,Wang Xiaohong,Peng Zhihui,Hou Yaming(Institute of Traditional Materia Medica,Hunan Academy of TCM,Changsha 410013);The effects of Xuming Tang on cerebrovascular osmosis and brain tissue pathology in the cerebral ischemic rats[J];PHARMACOLOGY AND CLINICS OF CHINESE MATERIA MEDICA;1997-06
Chinese Journal Full-text Database 10 Hits
1 Zhang Chengying, Miao Hua, Chen Qianfen, Tian Hecun(Department of Anatomy, Department of Pathophysiology,Bengbu Medical College, Bengbu 233003);ANATOMIC OBSERVATION ON MIDDLE CEREBRAL ARTERY MODEL OF CEREBRAL ISCHEMIA IN RAT[J];Chinese Journal of Anatomy;1998-03
2 ZHOU Yingchun 1, SHAO Nianfang 2, LIU Zhaoping 3 (1.Doctorate Postgraduate of Grade 97,Guangzhou University of TCM,Guangzhou 510405,China;2.Shandong University of TCM, Shandong 250011,China;3.Shandong Pharmacological Center of New Drug, Shandong 250;An Experimental Study of Naomai Tong Oral Liquid for Acute Ischemic Stroke[J];JOURNAL OF GUANGZHOU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE;1999-04
3 WT5BZ]Zhang Chengying Chen Qianfen Tian Hecun Department of Anatomy,Department of Pathophysiology,Benbu Medical College,Benbu 233003;Selection of Vascular Obstruction Site for Experimental Model of Focal Cerebral Ischemia on the Rat.[J];SICHUAN JOURNAL OF AUATOMY;2000-03
4 Zhang chengying Chen qianfen Tian hecun Department of Anatomy,Department of Pathophysiology, Benbu Medical Colleng,Benbu233003;Selection of vasualar ligution site for experimental model of focal cerebral ischemia on the rat.[J];Sichuan Journal of Auatomy;2002-01
5 HUANG Zhi-jian,LU Li-ming(College of Animal Science,Fujian Agriculture and Forestry University,Fuzhou 350002,China);Pharmacokinetics of Compound HuangBo Granule in Mice[J];Acta Veterinaria et Zootechnica Sinica;2006-01
6 ZHAO jin-ming,LIU shi-jun,LI-wei,et al.(The Laboratory of Pharmacology,The Institute of Taditional Chinese Mdicine in Liaoning,Shenyang 110031,China);The Protective effect of Hsy(safflor yellow) on Experimental rats with Cerebralischemia[J];Medical Recapitulate;2006-14
7 WANG Li,WU Ya jing,LI Feng et al The First Hospital of Jilin University,Jilin Changchun 130021〔;Protective effects of diemailing injection on experimental cerebral ischemia in rats[J];Chinese Journal of Gerontology;2001-03
8 LI Jiang-bin1,ZHANG Zhuang2,LI Yue-qing2,YAN Yan-fang2,ZHANG Zhi-hong1,NA Yan-qun1,GUO Ying-lu1 (1 Department of Urology,The First Hospital of Peking University, Institute of Urology,PeKing University,100034 2 The Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine,100700);To Determine the Serum Consentration of Berberine in Rabbits in RP-HPLC[J];Chinese Journal of Experimental Traditional Medical Formulae;2003-03
9 Geny Dongjin,et al.Department of Neurology,Ruijin Hospital,Shanghai the Second Medi-cal University. Shanghai. 200001;The dynamically changes of the concentrations of extracellular Na~+,K~+ and Ca~+ in cerebral infarct areas of the rats in vivo.[J];Chinese Journal of Nervous and Mental Diseases;1992-04
10 YU Chang-yuan1,TIAN Yong-li2 (1.College of Life Science and Technology in Beijing University of Che mical Technology,Beijing 100029; 2.Jiangsu Province Hospital of TCM,Nanjing,210029);Effect of DANQI Granules on Focal Injury of Cerebra l Vessels in Rats and Gerbilles[J];China Journal of Basic Medicine In Traditional Chinese Medicine;2005-09
Chinese Journal Full-text Database 10 Hits
1 Liu Ping 1,Wang Jinliang 1,Wang Yan 2,et al (1Pharmacology Department, General Hospital of PLA;2College of Chinese Materia Medica, Capital University of Medicine Sciences);Study on Dosage Application of Herbs in Class Formulas of KaixinSan and Their Actions on Depression[J];China Journal of Traditional Chinese Medicine and Pharmacy;2005-05
2 wangjian, et al;Effection of blood vigor of SOD on mice treated by single ginseny and Ding Zhi Xiao wan[J];;1994-03
3 ;Methodological evaluation of the studies of vascular dementia[J];Acta Academiae Medicinae Militaris Tertiae;2004-17
4 Zhang Baoping,Tang Jincao,Liu NanZhengzhou Municipal Center Hospital, Henan, Zhengzhou, China, 450007;The Effect of Jianlnaofuzhi Oral Liquid on Catalase and ATPase of Brain Tissue in Vascular Dementia Rat Model[J];Journal of Henan University of Chinese Medicine;2006-05
5 Shou DiWu, Zhang CHongQuan, Yang Ying, et al (Hunan Academy of Traditional Chinese Medicine, Changsha Hunan 410006);Experimental Study of the Influence of Jiannaotongluo Recipe on Cerebral Histopathology of Vascular Dementia Rats[J];Journal of Hunan College of Traditional Chinese Medicine;2001-01
6 Wang Feng 1, Xue Xingtao 2, Zheng Shaozhou 3 (1. Traditional Chinese Medicine Hospital of Henan Province, Zhengzhou, Henan, 450002; 2. Criminal Department Public Security Bureau of Yuanyang County, Yuanyang, Henan, 453500; 3. the First Affiliated Hospital of Henan College of Traditional Chinese Medicine, Zhengzhou, Henan, 450000);Influence of Tonifying the kidney and Promoting Blood Circulation by Removing the Phlegm on the Oxygen Free Radical and Tumor Necrotic Factor of the vascular Dementia Rat.[J];Henan Traditional Chinese Medicine;2004-02
7 Huang Hongli,Chen Baojian,Wu Yongping. (Institute of Cerebrovascular Disease of Xuzhou,Xuzhou 221002);Research of ET-1,NO in Plasma and the Blood-brain Barrier Permeability before Transient Ischemia-like Attack[J];Nervous Diseases and Mental Hygjene;2004-05
8 Sun Ming; Wu Qizhuan; Han Guilan; JiaZhong(Department of Neurology,the First Hospital of Beijing Medical University);Chemical Basis of Cerebral Ischemia-like Attack Induced by Peroxide in Kunming Mice[J];BASIC MEDICAL SCIENCES AND CLINICS;1999-06
9 Meng Ge, Zhu Langbiao, Zhao Yali et al. General Hospital of PLA, Beijing 100853;EFFECT OF ISCHEMIC PRECONDITIONING ON THE EXPRESSION OF HSP-70 MRNA IN POSTISCHEMIC SPINAL CORD OF RABBITS[J];Medical Journal of Chinese People's Liberation Army;2002-07
10 LI Peng-tao, PAN Yan-shu, HUANG Qi-fu,et al (Pathology Teaching Section of Beijing University of Chinese Medicine, Beijing 100029,China);Effect of Jiedu Tongluo Fang on Synaptic Plasticity in Hippocampus After Cerebral Ischemic Injury[J];Progress of Anatomical Sciences;2002-02
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 ZHANG Hai-Ning,SUN Li,TANG Yue-Yu,WANG Ming-Yu,WU Jiang.Department of Neurology,First Hospital,Jilin University,Changchun 130021,China;Effects of Naomaitai Capsule on cerebral blood flow and apoptosis of hippocampus neuron in rats with vascular dementia induced by chronic forebrain ischemia[J];Journal of International Neurology and Neurosurgery;2009-04
2 CHANG Hong-juan,WANG Xuan,TONG Zhao-lei.Department of Neurology Medicine,the Second People′s Hospital of Xinxiang,Xinxiang 453002,China;Study of Clinical and Hemorrheology on Naomaitai capsule in Treatment of TIA[J];Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease;2010-10
【Secondary Citations】
Chinese Journal Full-text Database 5 Hits
1 Ma Shushi et al Dept. of Pathology, Beijing Medical University, Beijing;Ultrastructure of the neurons in Ischemic Hypoxia in Rabbits[J];Chinese Journal of Clinical and Experimental Pathology;1989-01
2 Lu Guo-cai, Yuan Bo-jun, Zhou Gang (Second Military Medical University, Shanghai, 200433);The Effects of XING NAO YING On Hemorheology[J];Chinese Journal of Hemorheology;1994-04
3 WU Jun-Fang;SHI Yi-Ju; LIU Tian-Pei(Department of Pharmacology,Nanjing Medical University,Nanjing 210029;Department of Pharmacology,Tai'an Medical College,Tai'an 271000);Protective effcts of berberine on cerebral ischemia in mice and rats[J];CHINESE JOURNAL OF PHARMACOLOGY AND TOXICOLOGY;1995-02
4 Jiang Xijiu,et al.(The Second Military Medical Univeroity,Shanghai,200433);An Experimental Study on the Effect of Xingnaoyin[J];TRADITIONAL CHINESE DRUG RESEARCH & CLINICAL PHARMACOLOGY;1994-03
5 Chen Lifeng, Wu Jinsong (Institute of Traditional Materia Medica, Hunan Academy of TCM, Changsha 410006);The Effcts of Antiagglutination of Xuming Tang and It on the Cerebral Blood Flow[J];Pharmacology and Clinics of Chinese Materia Medica;1991-06
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