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《China Journal of Traditional Chinese Medicine and Pharmacy》 2005-07
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Prevention Action of Changtong Oral Liquid on Postoperative Intestinal Adhesions in Rabbits

Wang Chunxia Hou Lianbing (Nanfang Hospital, Southern Medical University)  
Objective: To observe the Prevention Action of Changtong Oral Liquid (CTOL) on the postoperative intestinal adhesions in rabbits. Method: Thirty-six male New Zealand rabbits were randomly divided into six equal groups (n=6): Normal control (group 1); model control (group 2); Simo Decoction (group 3); and CTOL minimal, medium and maximal dosages (group 4,5,6). Except group 1, the other rabbits were created as intestinal adhesive models. Group 1 and group 2 were orally fed with distilled water (20ml/kg), and group 3 to 6 with Simo Decoction 10ml/kg and CTOL in doses of 2.15g/kg, 4.30g/kg and 8.60g/kg respectively. On day 3 after surgery, the blood samples were collected to determine the fibrinolytic activity, and on day 9 the adhesion was graded. Result: CTOL could evidently reduce the severity of postoperative adhesions and increase plasma tPA activity and inhibit plasma PAI-1 activity. Conclusion: CTOL could prevent postoperative intestinal adhesion formation.
【Fund】: 国家重点科技攻关项目(No:9690105245)
【CateGory Index】: R285.5
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【References】
Chinese Journal Full-text Database 1 Hits
1 WANG Chun-xia1,ZENG Xu-xin2,HUO Qi-lu1,HOU Lian-bing1(1Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;2 Fushan University,Fushan 510000,China);Effect of ChangTong oral liquid on the cell cycle of cultured fibroblasts from normal peritoneum and adhesion[J];China Journal of Traditional Chinese Medicine and Pharmacy;2009-07
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1 Wang Chun-xia1,Zeng Xu-xin2,Huo Qi-lu1, Hou Lian-bing1 1 Department of Pharmacy,Nanfang Hospital, Southern Medical University, Guangzhou 510515, China; 2 Fushan University, Fushan 510000, China;;Effect of CTOL on the Cell Cycle of NF and AF[A];[C];2009
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