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《China Journal of Traditional Chinese Medicine and Pharmacy》 2008-07
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Study on synthesis and liberation of NO and IL-1β from fascia tissue cells of rat under pressure stimulation in vitro

CHEN Bo1,XIE Xi-mei1,JIA Ying2,LV Ming-zhuang2(1Guiyang College of TCM,Guiyang 550002,China;2Guiyang Medical College,Guiyang 550004,China)  
Objective:To provide some experimental basis of cell biomechanics for clinic treatment of massage by exploring synthesis and liberation of NO and IL-1β from fascia tissue cells of rat under pressure stimulation in vitro.Methods:Fascia tissue cells of rat were cultured in vitro.After morphological identi cation,50kPa pressure was forced on these cells,then the contents of NO and IL-1β in culture medium were detected.Results:The fascia tissue cells are mainly made up of broblast cells.The contents of NO and IL-1β in culture medium were both increased signi cantly under pressure stress.Conclusion:Fascia tissue cells can receive the mechanical stimulation,and transform the mechanical signals into biological signals.The reaction to mechanical stimulation may be one of the cell biomechanical principles of massage.
【Fund】: 贵州省科技厅科技基金项目(No.黔科合J字2006[2063]号)
【CateGory Index】: R244.1
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