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《China Journal of Traditional Chinese Medicine and Pharmacy》 2010-07
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Clinical observation of Xiao'ai Jiedu Prescription combined with chemotherapy on advanced cancer

ZHOU Hong-guang1,CHEN Hai-bin1,WU Mian-hua1,WANG Rui-ping2,WANG Li2, LU Wei2,ZHANG Yu3 (1Nanjing University of Chinese Medicine,Nanjing 210029,China; 2Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China; 3Provicial Integrated Traditional and Western Medical Hospital,Nanjing University of Chinese Medicine,Nanjing 210029,China)  
Objective:To observe the efficacy and safety of Xiao'ai Jiedu Prescription combined with chemotherapy on advanced cancer.Methods:198 Cases of stage Ⅲ-Ⅳ cancer chemotherapy patients were divided into chemotherapy and traditional Chinese medicine group (treatment group),chemotherapy alone group (control group).The treatment group was given Xiao'ai Jiedu Prescription during the chemotherapy period,lasted for 3 months. Results:Compared with the control group,short-term effective ratio were 69.38%,32.14%,chemotherapy completion rates were 97.69%,66.36%,difference between the two groups was statistically significant (P0.05).The quality of life and immune function of treatment group were significantly higher,and the toxicity was lower than the control group.Difference between the two groups was statistically significant (P0.05,P0.01).Conclusion:Xiao'ai Jiedu Prescription raised short-term clinical efficacy for advanced cancer and reduced the toxicity of chemotherapy drugs and significantly improved the quality of life of patients.So,Xiao'ai Jiedu Prescription was a anticancer drug with good developmental prospects.
【Fund】: 国家自然科学基金项目(No.30973742/C190201);; 江苏省自然科学基金项目(No.BK2007240);; 江苏省高校自然科学研究面上项目(No.09KJB360003);; 江苏省普通高校研究生科研创新项目(No.CX09S_037Z);; 江苏省中医药局科技项目(No.LB09032)~~
【CateGory Index】: R730.5
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