Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《China Journal of Traditional Chinese Medicine and Pharmacy》 2011-07
Add to Favorite Get Latest Update

Effects of Huanglianjiedu-Decoction on blood pressure and inflammatory factors in spontaneous hypertension rats

ZHANG Zhi-wei,YUE Gui-hua,ZHANG Ai-zhen(Ruikang Hospital of Guangxi TCM University,Nanning 530011,China)  
Objective: To research the variety of the inflammatory factors and blood pressure of Spontaneous Hypertension Rats(SHR) with Huanglianjiedu-Decoction,and discuss the mechanism to cure hypertension.Method: 24 12-week-age male SHR were divided into three groups-Huanglianjiedu-Decoction group,the model group and Captopril group in random,treated for 6 weeks,tested the changes of the blood pressure pre and post the treatment separately,measured the density changes of the hs-CRP,6-K-PG,ET-1,vWF,Hcy,MCP-1 by ELLSA and NO by nitrous reductase chromatometry for those rats,and compared with 8 WKY rats in the same age for blank control.Results: The blood pressure of SHR increased progressively.The hs-CRP.ET-1.vWF.Hcy and MCP-1 increased,and 6-K-PG and NO decreased in the SHRs' plasma.Huanglianjiedu-decoction group could control the blood pressure of the SHR,decrease the content of the hs-CRP,Hcy,ET-1,vWF and MCP-1,and increase the content of the 6-K-PG and NO.Conclusion: Using Huanglianjiedu-decoction could improve the inflammatory response and control the hypertensive in the SHR.
【Fund】: 广西科学基金项目(No.桂科自0832177)~~
【CateGory Index】: R285.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 7 Hits
1 ZHANG Ling-duan,REN You-hong,MA Xing-rong(The First affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China);Study on relationship between TCM syndrome types and plasma homocysteine in patients with essential hypertension[J];China Journal of Traditional Chinese Medicine and Pharmacy;2008-12
2 HAN Xue-jie,DING Yi,WANG Li-ying,YUWEN Ya,SHI Nan-nan(Director:SHEN Shao-gong)(Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China);Study on interrelation between hypertension inflammatory factors and phlegm-stasis[J];China Journal of Traditional Chinese Medicine and Pharmacy;2010-03
3 CHEN Zi-li ZHENG Ji-ping YANG Fei ZHAO Xu Department of Cardiology,The First Hospital of Taizhou,Taizhou,Zhejiang,318020,China;Correlation between high-sensitive C-reactive protein and hypertension[J];Chinese Journal of Cardiovascular Rehabilitation Medicine;2006-02
4 YANG Jian, WANG Wei-shu. Department of Cadre Healthcare, Second Hospital of Shanxi Medical University, Taiyuan 030001, China;Corrdation among tumor necrosis factor alpoha, high sensitivity C-reactive protein and homocysteine in senile essential hypertension pertensive patients[J];Chinese Remedies & Clinics;2007-10
5 HOU Jin-chao,WANG Fa-liang,BO Ai-hua.(Department of Electron Microscope Experimental center,Hebei North University,Zhangjiakou 075029,China);Progress of C-reactive Protein and the endothelial Dysfunction Markers of Essential Hypertension[J];Medical Recapitulate;2008-23
6 LIU Lei2, JIANG Peng1, DOU Sheng-shan1, LIU Run-hui1, ZHANG Chuan1, ZHANG Wei-dong1 (1.School of Pharmacy, Second Military Medical University, Shanghai 200240, China; 2.Hunan University of Traditional Chinese Medicine, Changsha 410007, China);Advances in studies on chemical constituents in Huanglian Jiedu Tang and their pharmacology[J];Chinese Traditional and Herbal Drugs;2008-06
7 Wu Shuzhen,Zhao Luosha,Fan Ping Department of Cardiology,The Second People's Hospital,Zhengzhou(Zhengzhou 450000);Effects of Losartan on Monocyte Chemoattractant Protein-1 in Hypertensive Patients[J];Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease;2008-09
【Co-citations】
Chinese Journal Full-text Database 8 Hits
1 LIU Lin-lin1,GUO Rong-juan2,ZHANG Yun-ling2(1Dongzhimen Hospital Affliated to Beijing University of Chinese Medicine,Beijing 100700,China;2Dongfang Hospital Affliated to Beijing University of Chinese Medicine,Beijing 100708,China);Relationship between syndrome factor of hypertension and interleukin-6,highly sensitive C-reactive protein and matrix metalloproteinase-9[J];China Journal of Traditional Chinese Medicine and Pharmacy;2011-07
2 YUE Gui-hua,ZHANG Zhi-wei,MENG Zi-yu,et al.Affiliated Ruikang Hospital,Guangxi TCM U- niversity,Nanning 530001,China;Effects of Huanglianjiedu-Decoction on inflammatory factors,von-willebrand factors of young age SHR[J];Global Traditional Chinese Medicine;2010-01
3 Wang Ruiying(Tianjin chest hospital,Tianjin 300051);Angiotension Ⅱ receptor blocker's clinical signification for the patients with Isolated systolic hypertension[J];Tianjin Pharmacy;2008-06
4 Xu Yan-zhi1, Yang Feng-ying1, Luo Dong-qing2 1Department of Stomatology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, Hebei Province, China; 2Department of Stomatology, Bejing Hospital of Traditional Chinese Medicine, Capital Medical University, Bejing 100010, China;Effects of Shuanghuangbu on proliferation activity of human periodontal ligament cells cultured in vitro[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2009-37
5 SHOU Guang-li,CAI Xin(Department of Cardiology,The First Affiliated Hospital of Bengbu Medical College,Bengbu 233004,China);Advancements in Understanding of Relationship Between TNF-α and Essential Hypertension[J];Advances in Cardiovascular Diseases;2010-03
6 HE Yuan Department of Medicine,Geriatric Hospital of Fujian Province,Fuzhou,Fujian,350003,China;Effect of bisoprolol and its influence on concentration of C-reactive protein in aged patient with angina[J];Chinese Journal of Cardiovascular Rehabilitation Medicine;2007-06
7 DENG Yuan-xiong1,3,LIU Xiao-dong2,LIU Li2,CHEN Yu-shuang1(1.College of Medicine,Hunan Normal University,Changsha 410013,China; 2.Key Laboratory of Drug Metabolism and Pharmacokinetics,China Pharmaceutical University,Nanjing 210009,China;3. Key Laboratory of Chemical Biology and Traditional Chinese Medicine Analysis,Ministry of Education,Hunan Normal Univesity,Changsha 410081,China);Effects of Huanglian Jiedu Decoction on activities of intestinal disaccharidases in diabetic rats[J];Chinese Traditional and Herbal Drugs;2010-07
8 YU Xin, YAO Guang-hui, YU Xi-ran, et al. Deparment of Cardiology, Sanming First Hospital, Fujian, Sanming 365000, China;The Relation of Non-rheumatic Atrial Fibrillation and C-reactive Protein[J];Chinese Journal of Prevention and Control of Chronic Non-Communicable Diseases;2007-03
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 HAN Xue-jie1,LIU Ying1,(WDAirNeGct oLri:-SyHinEgN1,JSIAha Ho-agio-hnuga1)2,LIAN Zhi-hua3,DING Yi1(1Institute of Clinical Basic Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China;2Institute of Basic Theory of TCM,China Academy of Chinese Medical Sciences,Beijing 100700,China;3Journal of Traumatology and Orthopedics,China Academy of Chinese Medical Sciences,Beijing 100700,China);Theorectical study on the relationship between hypertension and combined phlegm and blood stasis and f ive zang viscera[J];China Journal of Traditional Chinese Medicine and Pharmacy;2009-03
2 WANG Ling, ZHOU Ying-ling, LIN Shu-guang Institute of Cardiovascular Diseases of Guangdong Province, Guangzhou 510100, China;Association between angiotensin converting enzyme I/D polymorphism and high-sensitivity C-reactive protein in type 2 diabetic patients with atherosclerosis treated with ramipril[J];Journal of First Military Medical University;2005-06
3 Wu Yan , Sun Jianning, Shi Renbing (College of Traditional Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100102);Effects of the Active Fraction of Huanglianjiedu Decoction on Lipid Peroxidation Damage in the Rat with Multiple Cerebral Infarction[J];Journal of Beijing University of Traditional Chinese Medicine;2004-06
4 Lei Yan, Huang Qifu , Wang Yongyan (Beijing University of Traditional Chinese Medicine, Beijing 100029) T6;Pathologic Basis of Collateral Disease Formation[J];JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE;1999-02
5 LI Ai Min, HE Zuo Yun, ZHOU Xiao Bo, QIN Jun, and GENG Jian-Meng [WT6BX](Xinqiao Hospital of Third Military Medical University,Chongqing 400037,Chnia);Effects of Angiotensin Ⅱ on Protein and mRNA Expression of Monocyte Chemoattractant Protein-1 in Cultured Rabbit Aortic Smooth Muscle Cells[J];Chinese Journal of Arteriosc Lerosis;2001-02
6 CHEN Mei-Fang,XIE Xiu-Mei,YANG Tian-Lun,CHEN Zhi-Xiong,and LI Yuan-Jian(1.Department of Cardiovascular Medicine,Xiangya Hospital,Central South University,Changsha 410008;2.Department of Pharmacology,School of Pharmaceutical Sciences,Central South University,Changsha 410078,China);Inhibitory Effect of Losartan on Monocytic Activation via Downregulation of Monocyte Chemoattractant Protein-1 Receptor Expression[J];Chinese Journal of Arteriosclerosis;2007-01
7 WANG Bangning,ZHANG Fengxiang, SONG Bing,CHEN Danian,LIU Hejun,LIU Min,LUO Zhigang(Department of Cardiovascular Medicine,The First Affiliated Hospital of Anhui Medical University,Hefei 230022 ,China);The effect of bisoprolo on plasma C-reactive protein patients with coronary heart disease.[J];;2005-02
8 MA Hong,ZHANG Qi-Yi,WANG Yun-Ying.(Qingdao Municipal Hosp.,Qingdao 266011,China);Endothelium dysfunction and prethrombotic state in essential hypertension[J];Ningxia Medical Journal;2006-06
9 Kuang Zaoyan, LIU Qianxian (Dept. of Microbiology and Parasitology, Guangzhou University of TCM, Guangzhou 510405, China);Effect of Huanglian Jiedu Decoction on Serum Interleukin-2 in Mice Attacked by D-galactosamine and Lipopolysaccharide[J];JOURNAL OF GUANGZHOU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE;1999-03
10 WU Hui, LIU Yude, WU Wei, DONG Yugang (Advisor: HUANG Yanshou) (The First Affiliated Hospital, Guangzhou University of TCM, Guangzhou 510405, China; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510089, China);Preventive Effect of Heat-clearing and Toxicity-removing Method on Rabbit Atherosclerosis Induced by Chlamydia Pneumoniae Infection[J];Journal of Guangzhou University of Traditional Chinese Medicine;2006-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved