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《China Journal of Traditional Chinese Medicine and Pharmacy》 2013-11
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Study on the effect of resveratrol against RSV in vitro

XIE Xiu-chun;XU Jian-ya;WANG Shou-chuan;Nanjing University of Chinese Medicine;  
Objective:To investigate the effect of resveratrol against respiratory syncytial virus(RSV) through experiments of in vitro.Methods:The cell survival rates of resveratrol in the treatment,prevention,direct inhibition of three kinds of mode were measured by cytopathic effect reduction assay and MTT assay,when Hep-2 cell was infected with RSV and the antiviral effect of resveratrol with ribavirin as the positive control drug.Results:The three of actions have a certain degree of inhibition,therapeutic effect and preventive effect,which is more pronounced.In preventive effect mode,the CPE was typically reduced in resveratrol group compared with ribavirin group;in therapeutic effect mode,the virus inhibition rate of resveratrol group was higher compared with RSV infected group(P0.05).Conclusion:Resveratrol may have some protection against RSV in vitro.
【Fund】: 国家自然科学基金项目(No.81072840);; 高等学校博士学科点专项科研基金(No.20103237110003)~~
【CateGory Index】: R285.5
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