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《北京医科大学学报》 1989-03
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STUDIES OF ACTIVE POLYSACCHARIDES OF GANODERMA LUCIDUM

School of Pharmaceutical Sciences He Yunqing, Li Rongzhi, et al  
The "Ling zhi" polysaccharides BN3C have been isolated from the fruit bodies of Ganoderma Lucidum. BN3C showed some activities in "Fuzhen Guben" effect. Four homogeneous polysaccharides have been isolated from the BN3C. They are named "Ling zhi" polysaccharide BN3C1, BN3C2, BN3C3, BN3C4.According to IR data and acid hydrolysis, BN3C1 was identified as a β-glucopyranose. Their structures have been elucidated mainly by periodate oxidation and Smith degradation. The glucan has a structure as β-(1→6) (1→3) glucopyranose.BN3C3 was identified as a heteropolysaccharide, containing glucose and arabinose, their molecular ratio of the two sugars was 4:1. BN,d has a structure as β-(1→6) (1→3) linkage, containing a small peptide moiety (5.4%). Amino acid components were cystine, tyrosine, leucine, glycine, γ-aminobu-tyric acid and other minor amino acids.
【Key Words】： Ganoderma Lucidum Ling Zhi polysaccharide Fuxhen Guben glucanpeptidosaccharide
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