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Clincal study of penehyclidime hydrochloride in the treatment of organic phosphorus poisoning

WU Hong Jing, LOU Bin Cheng, HUANG Dai Kun, LIU Qiu Jie (Department of Emergency, Peking Universty People's Hospital, Beijing 100044, China)  
Objective: To evaluate the efficacy safety and toxicity of penehyclidime hydrochloride in treatment of organic phosphorus poisoning. Methods: 17 cases patients with acute organic phosphorus poisoning were treated with penehyclidime hydrochloride in doses of 1-21 mg. Results: A total effective rate 100%was obtained with a tolerable side effect. The cure time was 18 hours~18 days, average 4.1 days. Conclusion: It is suggested by the result that Penehyclidime hydrochloride is a safe, highly effective, low toxicity anticholines agent in treatment of organic phosphorus poisoning.
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