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《Journal of Beijing Medical University》 2003-02
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Comparison and correlative analysis of pulmonary function markers after extracorporeal circulation

CUI Hujun 1△ , ZHANG Mingli 1, XIAO Feng 1, LI Yan 1,WANG Jin 1, CHEN Hongyi 2 (1. Department of Cardiac surgery, 2. Department of Thoracic surgery, Peking University First Hospital, Beijing 100034, China)  
Objective: To compare the clinic significance of three lung function markers after cardiopulmonary bypass operation. Methods: Twenty four patients who continuously took selective coronary artery bypass grafting (CABG) with cardiopulmonary bypass in our hospital were separated randomly to AT group and non AT group according the different treatments of the residue blood in extracorporeal circulation (ECC) circuit, 12 patients in each group.The data of hemodynamics and oxygenation after anesthesia induction and 1,6,24,48 h after ECC were recorded.Respiratory index (RI), oxygenation index (OI) and M index (P aO 2/P AO 2)were counted and compared at the same time. Results: CI, O 2ER , DO 2I and VO 2I were all elevated obviously after ECC, and Qs/Qt were decreased. There were no difference of all these markers between two groups. RI, OI and P aO 2/P AO 2 did not change during perioperation in AT group, but in non AT group, RI was increased after ECC, company with the decrease of OI and P aO 2/P AO 2 at the same time. Nevertheless there was no difference between two groups. But the alterations of the marker percentages were more obviously, there were marked differences between the percentages of RI and P aO 2/P AO 2 24 h after ECC.All three markers had correlation with Qs/Qt and VO 2I. Conclusion: RI,OI and P aO 2/P AO 2 all can reflect appropriately the change of lung function after extracorporeal circulation and the monitor of the develo pmental alterations individually may be more instructive in clinical practice.
【Fund】: 北京市科委重点项目 (95 2 0 90 10 0 )资助~~
【CateGory Index】: R654.1
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