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《JOURNAL OF BEIJING MEDICAL UNIVERSITY》 1994-02
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THE VARIATION IN CYTOSOLIC FREE CAICIUM,NUCIEOUS CALMODULIN AND DNA OF HUMAN GASTRIC CANCER CELLS UNDER THE ACTION OF LAMININ

Department of Cell Biology Xiao Junjun, et al  
hanges in the content of cytosolic Ca2+ and the nucleous calmodulin and DNA of human gastriccancer(BGC-823 )cells bound with and without external laminin(LN)were studied using a cytofluor- ophotometer The followIng results were obtained:Green annulus can be seen on the membrane of ca- ncer cells.When cells cultured on the LN coated glass surface,the content of cytosolic Ca2+ and the nucleous calmodulin increased obviously,accopanied by increase of DNA,which suggesrs that the cyto- solic Ca2+ may play a role of second messenger by means of CaM in the biological progress of LN promoting cancer cell proliferation
【Key Words】： Laminin Cytosolic free calcium Calmodulin Nuclear DNA Human gastric cancer cell line
【CateGory Index】： R735.2
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