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《JOURNAL OF BEIJING MEDICAL UNIVERSITY》 1996-02
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THE REGULATION OF LYCIUM BARBARUM POLYSACCHARIDE ON APOPTOSIS OF MOUSE THYMOCYTE IN VITRO

LIUYutao;ZNOUHe;BAIXiaowei ;YLNJinzhu(Department of Immunology. Beijing McdicalUniveraity 100083)  
Objective. The apoptosisofmurine thymocytes induced by DEX was regulated by LBP and OXY. Methods. PI staining. DNA fragmentation. DNA gel electrophoresis.and so on Results.LBP could inhibit fragmentation of DNA in murine thymocyte induced by DEX.The inhibition is dose-depen-dent and obvious. especially in 1 g/L.Ithas been shown that LBP could greatly reduce the rising of in tracellular Ca2+concentrathn induced by DEX or A23187 respectively.(%of inhibition .54 and 13).Conelusion. LBPcould inhibit the apoptosis induced by DEX.which OXY doesn’t have any effect on.
【Fund】: 中华洛氏基金
【CateGory Index】: R285.5
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