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《JOURNAL OF BEIJING MEDICAL UNIVERSITY》 1996-03
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STUDY OF DNA DAMAGE AND REPAIR IN RAT'S CATARACT INDUCED BY PINGYANGMYCIN

Ll Xianxi;HE Haiying; WANG Bo; ZHANG Jiaping; LIANG Kang;CHANG Changying(Department of Biochemistry and Molecular Biology,Beijing Medical University 100083)  
Objectlve:To study DNA damage and repair kinetics in the rat’s Pingyangmycin-induced cataract model.Metbods:Single Cell Gel Assay(SCG)technique.Results:It was observed that the very obvious DNA migration happened just 12 hours after the first injection of Pingyangmycin and continued during cataractogenesis.Conclusion:The result suggested that the mechanism of the cataract formation induced by Pingyangmycin was different from those in cataract induced by other inducers.
【Fund】: 国家自然科学基金
【CateGory Index】: R978.19
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【References】
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