Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
Add to Favorite Get Latest Update


WANG Yanrong, QIAN Rongli, MA Xiaowei(Department of Endocrinology, the First Hospital, Beijing Medical University, Beijing 100034)  
Objective: To study the activity of liver glycogen synthase in analogous model of NIDDM rats. Methods: 40 male Wistar rats were divided into two groups at random. Each group consisted of 20 rats. The rats of one group were injected with low dose of streptozotocin(STZ)(30 mg/kg)via tail vena. The rats of the other group used as control were not injected with STZ. The rats among the group were injected with STZ whose glucose tolerance was impaired and the level of insulin equal to or higher than that of the control. After 18 weeks they were taken as the analogous rat model of NIDDM. The activity of liver glycogen synthase (GS)was assayed at the end of the experiment. Results: Type I  enzyme: (0.18±0.06) μmol/(min·g )versus (0.24±0.09) μmol/(min·g) (P0.05), and totalenzyme: (1.5±0 .4) μmol/(min·g)versus (1.8±0.4) μmol/(min·g) (P0.05). Conclusion: The GS activity of diabetic rats was significantly lower than that of the control.
【Fund】: 国家教委回国人员启动基金
【CateGory Index】: R-332,R587.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 10 Hits
1 LIN Hua;NIU Yan-feng;LI Ling;ZHUANG Ao-bo;GAO Li-hui;Biomedical Engineering Research Center of Kunming Medical University;Medical College of Jilin University;;Hypoglycemic Effects of Mangiferin in Alloxan-induced Diabetic Mice[J];天然产物研究与开发;2016-10
2 MENG Xiao;JIANG Li-shi;QIAN Yu;KANG Jin-mei;CHEN Yan;WANG Juan;CHE Zhen-ming;School of Public Health,Chengdu University of TCM;School of Biological and Chemical Engineering,Chongqing University of Education;School of Food and Bioengineering,Xihua University;;Effect of Lactobacillus plantarum SCS1 on blood glucose levels in hyperglycemia model mice[J];食品工业科技;2016-02
3 Guo Shuxiang;Sun Dongmei;Li Jing;The Branch of Tangshan Gongren Hospital;;ULTRASTRUCTURAL DYNAMIC OBSERVATION OF MYOCARDIAL AND RENAL FIBROSIS IN TYPE 1 DIABETES MELLITUS RATS[J];中国煤炭工业医学杂志;2015-05
4 WEN Xiao-hong1,ZHANG Ren-dong,GUO Yang,ZHAO Yuan-yu,WANG Ya-ping,DAI Xiao-si(1 Basic Medical School,North Sichuan Medical College,Nanchong 637007,P.R.China);Change of blood glucose in rats model with damaged pancreas Islets[J];山东医药;2011-37
5 HAN Bao-Qin1,WANG Jian1,CAI Wen-Di2,SONG Fu-Lai1,LIU Wan-Shun1(1.College of Marine Life Sciences,Ocean University of China,Qingdao 266003,China;2.Weifang Medical University,Weifang 261053,China);Effects of Water-Soluble Low Molecular Chitosan on Plasma Glucose in Diabetic Rats[J];中国海洋大学学报(自然科学版);2011-Z1
6 WEN Xiao-hong,et al(Department of Histology and Embryology,School of Basic Medical Sciences,Chongqing Medical University);Dynamic observation on the intraperitoneal glucose tolerance test in the non-hyperglycemic rats treated with streptozotocin[J];重庆医科大学学报;2008-12
7 FU Li-juan,WANG Hong-xin,PANG Dong-bo,et al.Department of Pharmacology,Jinzhou Medical College,The First Hospital Affiliated to Jinzhou Medical College,Jinzhou 121001,China;The Change and Significance of Myocardial Apoptosis in the Process of Diabetic Myocardium Pathological Changes of Rats[J];中国微循环;2005-06
8 XIAO Mei-fang, ZHANG Xue-mei 1, BAI Xiang, TAN Huan-ran Department of Pharmacology, School of Basic Medical Science, Peking University, Beijing 100083, China; 1 Department of Pharmacology, School of Basic Medical Science, Dalian University, Dalian 116622, Liaoning, China;Comparative study on changes of glycogen metabolism in model mice of diabetes mellitus[J];中国临床药理学与治疗学;2005-06
9 Gao Yuanyuan Hu Xiaofang(College of Physical Education,Shanxi Normal University,Xi'an 710062);Chromium and Original Metabolism in Sugar in Sport[J];安徽体育科技;2005-01
10 WANG Jing1,BIAN Rong-wen2 (1.Nanjing University of Traditional Chinese Medicine,Nanjing 210029,China; 2.Jiangsu Provincial Geriatrics Research Insititute,Nanjing 210029,China);Advance of the relation in amylin and insulin resistance[J];现代医学;2005-01
Chinese Journal Full-text Database 10 Hits
1 YU Ren-Qiang;YUAN Jin-Ling;MA Lu-Yi;QIN Qing-Xu;WU Xiao-You;Department of Pediatrics, First Hospital Affiliated to Dalian Medical University;;Probiotics improve obesity-associated dyslipidemia and insulin resistance in high-fat diet-fed rats[J];中国当代儿科杂志;2013-12
2 CHEN Pei;DANG Hui;ZHANG Qiu-xiang;LIU Xiao-ming;ZHAO Jian-xin;CHEN Yong-quan;ZHANG Hao;CHEN Wei;State Key Laboratory of Food Science and Technology,Jiangnan University;College of Food Engineering and Nutritional Science,Shaanxi Normal University;School of Food Science and Technology,Jiangnan University;;Antidiabetic effect of Lactobacillus rhamnosus in high-fat-fed and streptozotocin-induced type Ⅱ diabetic mice[J];食品工业科技;2013-24
3 ZHANG Kuan-chao;MA Wan-yan;WEN Han;School of Life Science,Anhui Agriculture University;;Study on effects of polysaccharides from Camellia oleifera Abel. on decreasing blood sugar[J];食品工业科技;2014-02
4 Park Soo-hyun1,Sim Yun-beom1,Suh Hong-won1,Nam Kyung-sung3,Lee Dong-jin2,Choi Se-young2,Lee Deuk-sik2,3(1.Department of Pharmacology,Institute of Natural Medicine,College of Medicine,Hallym University,Gangwon-do 200-702,Korea;2.Life Science Institute,Well-being LS Co.,Ltd.Gangwon-do 210-340,Korea;3.Department of Food Service Industry,Hanzhong University,Gangwon-do 240-713,Korea);Effects of physiological activity on immune function,anti-hyperglycemia and intestinal motility promotion of vegetable Lactobacillus fermentum[J];中国微生态学杂志;2013-07
5 NIU Yan-fen1,GAO Li-hui1,LIU Xu1,LIN Hua2,ZHANG Yuan1,LI Ling1 (1.Biomedical engineering research center,Kunming Medical University;2.Yunnan Key Laboratory of Pharmacology for Natural Products,Kunming Medical University,Kunming 650500,China);Effects of mangiferin on uric acid levels and the function of the liver/renal in oxonate-induced hyperuricemic rats[J];中国药理学通报;2012-11
6 FAN Wen-ya,WU Zheng-jun*,GUO Ben-heng Technology Center of Bright Dairy Co.,Ltd..,Shanghai 200436,China;Research Advances in Hypoglycemic Activity of Lactic Acid Bacteria[J];天然产物研究与开发;2012-09
7 MA Jie-tao,ZHANG Ling,LAI Wei-qing,LU Ming-yang,LIU Zheng,WANG Yin Zhejiang Academy of Medical Sciences,Hangzhou,Zhejiang 310013,China;The effect of mangiferin on glucose consumption of L6 cell and the study of its molecular mechanism[J];中国预防医学杂志;2012-09
8 WANG Xue,WEN Shu,LI Hua-jun,YUAN Jie-li(Department of Microecology,Dalian Medical University,Dalian 116044,China);Effect of Lactobacillus acidophilus on the prevention and treatment of typeⅡ diabetes in mice[J];中国微生态学杂志;2010-12
9 LUO Cheng,LU Xiao-xiang*,ZHOU Da(Biotechnology and Food Science College,Tianjin University of Commerce,Tianjin Key Laboratory Food of Biotechnology,Tianjin 300134,China);Study on hypoglycemic function of cantharellus polysaccharide[J];食品工业科技;2010-12
10 CHU Fu-di HUANG You-min,ZHANG Dong-mei,ZHANG Min.Department of Clinical Laboratory,Central People's Hospital of Tengzhou,Tengzhou 277500,China;Correlation among diabetic nephropathy,resistin and supersensitive C reaction protein[J];中国医药;2010-01
【Secondary References】
Chinese Journal Full-text Database 7 Hits
1 LI Yugen;LI Jinming;MA Li;GUO Yang;DENG Xianzhong;YANG Zhengwei;Department of Urological Surgery,Affiliated Hospital of North Sichuan Medical College,North Sichuan Medical College;Department of Histology and Embryology,North Sichuan Medical College;Morphometric Research Laboratory,North Sichuan Medical College;;A quantitative study of the effect of STZ-induced hyperglycemia on histological structures of seminal vesicles in mature rats[J];中国体视学与图像分析;2018-01
2 ZHENG Xiaowei;SHEN Xuemei;ZHANG Zijian;LIU Yangliu;DONG Zhizhong;CHEN Bo;Beijing Key Laboratory of Nutrition,Health and Food Safety,Nutrition & Health Research Institute,COFCO Corporation;;Application of probiotics in glycemic control:Research progress[J];中国微生态学杂志;2018-02
3 CHAI Zheng;DING Yi;Shunyi Branch,Beijing Chinese Medicine Hospital;;Impacts of Shengji Cataplasm on Wound Healing and Relevant Healing Factors in the Mice with Diabetic Skin Ulcer[J];世界中西医结合杂志;2017-10
4 ZHANG Jifeng;LIU Xiuli;TIAN Wenjing;SUN Ruzhi;TIAN Fengsheng;Cangzhou Medical College;Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine;;Effect of Sanhuang Yishen Capsule on streptozotocin induced myocardial and renal tissue structure in diabetic rats[J];现代中西医结合杂志;2017-17
5 NI Qing;WANG Sheng-yi;HUANG Jing;Department of Endocrine,Guang'anmen Hospital,China Academy of Chinese Medical Sciences;;Effect of qi-benefiting and blood-circulation activating herbs on myocardial apoptosis in rats with diabetic myocardiosis[J];北京中医药;2016-06
6 WAN Xin;HE Jianping;ZHANG Huan;LIN Linghui;ZHANG Tian;FEI Yu;Department of Cell Biology,School of Basic Medicial Sciences,Jilin University;Department of Pathogenic Biology and Immunology,Xingtai Medical College;Department of Cardiology,Second Hospital,Jilin University;;Effects of low molecular weight chitosan on ClC-3 expression in cardiomyocytes of rats with hypoxia-reoxygenation injury[J];吉林大学学报(医学版);2016-03
7 CHAI Zheng;LI Dayong;LYU Yanwei;Liaoning University of Traditional Chinese Medicine;;Effects of Yixiao Ointment on Healing Related Factors in New Granulation Tissue of Mice with Diabetic Skin Ulcers[J];辽宁中医药大学学报;2016-07
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved