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《JOURNAL OF BEIJING MEDICAL UNIVERSITY》 1998-03
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EFFECTS OF erbB-2 REPRESSION AND EGF STIMULATION ON THE LEVEL OF STAT1 AND CYCLIN D1 PROTEIN

JIANG Kun#, QIN Yue, TONG Tanjun(#Department of Biochemistry and Molecular Biology, Beijing Medical University, Beijing 100083)  
Objective: To investigate the protein level of STAT1 and cyclin D1 following EGF stimulation before and after the repression of erbB-2 gene. Methods: Western blotting analysis of STAT1 and cyclin D1 following EGF stimulation before and after the decrease on erbB-2 expression. Results: Alteration on erbB-2 expression has little effect on the level of STAT1 upon EGF stimulation; induction of cyclin D1 upon EGF stimulation significantly decreased after the repression of erbB2. Conclusion: Decrease of erbB2 expression can suppress the EGFinduction of cyclin D1.
【Fund】: 国家自然科学基金
【CateGory Index】: R735.2
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【References】
Chinese Journal Full-text Database 3 Hits
1 Huang Jian-feng;Huang Ji-feng;Zhang Wei-cai;Department of Orthopaedics,Jingmen Municipal Shihua Hospital;Department of Orthopaedics,Wuhan General Hospital of Guangzhou Military Command;;Bone marrow mesenchymal stem cells differentiate into neuron-like cells induced by combination of two cytokines[J];中国组织工程研究;2014-06
2 WANG Zhi-feng,QIN Kun-ming,MO Kai,FU Dan-hui(Neurosurgery Department,The First Affiliated Hospital of Guangxi Medical University,Nanning 530021,P.R.China);The expression and its clinical significance of epidermal growth factor receptor in pituitary adenoma[J];微创医学;2011-02
3 YOU Qing jun,HU Guo qiang,YU Xue yan (Dept.of Thoracic Surgery,the Affiliated Hospital of Shandong Medical University);THE EFFECT OF 9-cis-RA ON c-erB-2 AND Rb GENE EXPRESSION IN HUMAN LUNG CANCER CELL LINES[J];山东医科大学学报;2000-04
【Co-references】
Chinese Journal Full-text Database 6 Hits
1 Hu Hui 1, 2 , Zhang Wei-cai 1, 2 , Huang Ji-feng 2 , Yan Qiong-jiao 3 , Yin Yi-xia 3 , Li Shi-pu 3 1 Graduate School, Southern Medical University, Guangzhou 510515, Guangdong Province, China 2 Department of Orthopedics, Wuhan General Hospital of Guangzhou Military Command, Wuhan 430070, Hubei Province, China 3 Research Center of Biomaterials and Engineering, Wuhan University of Technology, Wuhan430070, Hubei Province, China;Cytocompatibility between novel nerve conduit composite materials and bone marrow mesenchymal stem cells[J];中国组织工程研究;2013-16
2 KONG Yanguo, REN Zuyuan, SU Changbao, WANG Renzhi Laboratory of Neurosurgery Peking Union Medical College Hospital, Peking Union Medical College and Chinese Aacademy of Medical Science, Beijing 100730, China;Detection of serum epidermal growth factor receptor in the diagnosis of proliferation of pituitary adenomas[J];中华医学杂志;2002-08
3 SUN Xiu,CHEN Xian wen,CHEN Sheng di (Department of Neurology,Ruijin Hospital,Shanghai Second Medical University,Shanghai 200025)[;Influence of fibroblast growth factor and epidermal growth factor on proliferation and differentiation of neural stem cells[J];中国神经科学杂志;2000-02
4 DONG Guang Long, WANG Jun Yi, WANG Wei Zhong, JIA Tong Wen Department of Gastroenterological Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710033, China;Epidermal growth factor reduces gut bacterial translocation in parenterally fed rats following abdominal radiation[J];第四军医大学学报;2000-01
5 JIANG Kun#, QIN Yue, TONG Tanjun(#Department of Biochemistry and Molecular Biology, Beijing Medical University, Beijing 100083);EFFECTS OF erbB-2 REPRESSION AND EGF STIMULATION ON THE LEVEL OF STAT1 AND CYCLIN D1 PROTEIN[J];北京医科大学学报;1998-03
6 Zhao Peilin;Wang Huimin;Li Zhaote(Department of Histology and Embryology,Bijing Medical University,Beijing);EFFECT OF EXTIRPATION OF SUBMANDIBULAR GLAND ON GASTRIC MUCOSA IN RATS──A HISTOLOGICAL AND HISTOCHEMICAL OBSERVATION[J];解剖学报;1994-03
【Secondary References】
Chinese Journal Full-text Database 9 Hits
1 CHEN Juan;XIE Xi;PENG Yiran;YE Ying;XU Tie;Graduate School,Xuzhou Medical College;Department of Clinical Medicine,Xuzhou Medical College;Emergency Center,the Affiliated Hospital of Xuzhou Medical College;;Study on the directed differentiation of human cerebrospinal fluid-induced bone marrow mesenchymal stem cells into neuron like cells[J];徐州医学院学报;2016-04
2 Li Shasha;Lang Changhui;Peng Longying;Shu Xiaomei;Department of Pediatrics,the Affiliated Hospital of Zunyi Medical College;;Effect of cardiotrophin-1 mediated by recombinant adenovirus on the neural differentiation of bone marrow mesenchymal stem cells of rats[J];中华实用儿科临床杂志;2015-15
3 Zhi-yuan Guo;Xun Sun;Xiao-long Xu;Qing Zhao;Jiang Peng;Yu Wang;Institute of Orthopedics,Chinese PLA General Hospital;The Neural Regeneration Co-innovation Center of Jiangsu Province;;Human umbilical cord mesenchymal stem cells promote peripheral nerve repair via paracrine mechanisms[J];Neural Regeneration Research;2015-04
4 Zhang Hu-lin;Zhang Zi-qiang;Xu Hong-bin;Zhang Xiao-gang;Affiliated Hospital of Gansu University of Traditional Chinese Medicine;Baoji Municipal Hospital of Traditional Chinese Medicine;;Drynaria freeze-dried powder at different dosages influences proliferation and differentiation of rabbit bone marrow mesenchymal stem cells[J];中国组织工程研究;2014-41
5 Lan Jing;Yan Jin-yu;Xia Run-fu;Li Jian-feng;Rehabilitation Department, the Second Affiliated Hospital of Inner Mongolia Medical University;;Cistanche deserticola plus bone marrow mesenchymal stem cell transplantation for treating spinal cord injury in rats[J];中国组织工程研究;2014-41
6 LI Xiao-lei;WANG Xiao-qi;QU Hai-ou;Department of Surgery,The First People's Hospital of Wenling;;Effect of the combination of Weifuchun and retinoic acid on the expression of Rb gene and C- erbB- 2 gene in the patients with gastric precancerous lesions[J];中国临床药理学杂志;2014-06
7 ZHU Xiao-li,LIN Yong,TANG Jian-ying,ZHANG Zu-yi (Department of Respiratory Medicine,Zhongda Hospital,Southeast University,Nanjing 210009, China);The study on the relationship between expression of C-erbB-2 oncogene in non-small cell lung cancer and anticarcinogens treatment[J];现代医学;2004-06
8 REN Gui-jie~1, LIU Zhi-fang~1, DING Lei~1, HU Guo-qiang~2, HU Xiao-yan~1, TIAN Ke-li~1, YU Xue-yan~1(Institute of Biochemistry and Molecular Biology, Qilu Hospital, Medical College of Shandong University, Jinan 250012 China);Effects of 9- cis- retinoic acid on transcription of cyclin D1, cdk4 in lung adenocarcinoma cells[J];中国病理生理杂志;2004-03
9 REN Gui-jie,LIU Zhi-fang,DING Lei,et al(Dept.of Biochemistry and Molecular Biology,School of Medicine,Shandong University);Effects of9-cis-retinoic acid on expression of CyclinD1and Cdk4in non-small cell lung cancer[J];山东大学学报(医学版);2003-03
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