THE ROLE OF NUCLEUS RAPHE MAGNUS IN THE ANALGESIA OF PARAVENTRICULAR HYPOTHALAMIC NUCLEUS IN RATS
Kang Guoying,et al (Department of Physiology ,Binzhou Medical College)
The role of nucleus raphe magnus (NRM) in rats was studied. The changs of pain threshold after drugs were injected into PVN and NRM through pipes which had been buried previously were observed with behavior testing - pain method. The pain threshould increased obviously after i jccting sodium glutamate (10ug/ul) and hydrochloric acid morphine (10ug/ul) separately into PVN. This effect could be reversed by naloxone (2ug/ul) injected into NRM. The result suggests that NRM may be related to the analgesic process of PVN.