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《Journal of Binzhou Medical College》 2003-05
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Fan Chonglun,Xu Dongmei (Department of Internal Medicine,Jinan Central Hospital,Jinan 250013)  
Objective:In order to determine the therapeutic effects of large doses of heparin inhaled in the aerosol formation for the treatment of acute episode of severe asthma.Methods:Forty nine patients with acute episode of bronchial asthma were randomly divided into two groups .Large and small doses of groups of 28 and 21 cases were nebulized with 125 000 and 12 500 U of heparin dissolved in 20 mL saline respectively.Results:PEFR,FEV 1 and FEF% in the large doses group were markedly improved compared with those in the small doses group statistically,while the platelets,APTT and PT remained unchanged.Conclusion:Large doses of heparin can markedly improve pulmonary function with no apparent side effects.
【CateGory Index】: R562.25
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