Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Binzhou Medical College》 2004-04
Add to Favorite Get Latest Update

EXPERIMENTAL RESEARCH ON CHANGES OF FACILITATIVE INFLAMMATORY CELL FACTORS AND INFLAMMATORY CELLS IN SEPTICEMIC RATS

SHI Zengli,LIU Feng,YU Xiaoling, et al (Department of Pathophysiology,Binzhou Medical College,Binzhou 256603)  
Objective:To detect the changes of facilitative inflammatory cell factors (IL 8,TNF α) in blood plasma and inflammatory cells in peripheral blood and abdominal effusion at different periods of time in septicemic rats.Methods:Septicemia models were replicated by means of cecum ligature puncture,the levels of IL 8 and TNF α were measured by enzyme linked immunosorbent assay (ELISA) and the leucocytes in peripheral blood and abdominal effusion were counted under microscope after rats' blood and abdominal effusion were taken at 0,8 and 16 hours post experimentally.Results:In septicemia group,levels of IL 8 and TNF α at 8 and 16 hours after the experiment were noticeably higher than those at 0 hour ( P 0 01) post experimentally with that at 8 h more evident;IL 8 and TNF α levels of septicemia group at 8 and 16 hours were obviously higher than those of control group on which sham operations were done ( P 0 05).The number of leucocyte in peripheral blood of septicemic rats at 8 and 16 hours post experimentally was much lower than that at 0 hour ( P 0 01) with a trend of progressive decrease ,and the number in abdominal effusions had a trend of progressive increase ( P 0 01).Conclusion:IL 8 and TNF α may play a major role in the course of rats' septicemia and the abnormal distribution of inflammatory cells of septicemic rats is closely related to IL 8 and TNF α.
【CateGory Index】: R5153
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ZENG Dong-zhu, YU Pei-wu, MA Hong-min (Department of General Surgery, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Role of platelet activating-factor and its antagonist in serious intra-abdominal infection of the rats[J];Acta Academiae Medicine Militaris Tertiae;2001-08
2 Liang Zhongpei; et al(Department of Pathophysiology Guangzhou Medical College);The Change of Serum Nitric Oxide (NO) in Septic Rat and Its Significance[J];ACADEMIC JOURNAL OF GUANGZHOU MEDICAL COLLEGE;1997-05
3 Yang Junke; Wu Saizhu.( Department of cardiology disease, Nangfang Hospital, Guangzhou 510515 )Zhou Kexiang; Shi Xinhua.( Pharmacutical of first Military Medical University, Guangzhou 510515 )Peng Shiqi.(The Sino-Germany Joint laboratory of Beijing Medica;The Blood Pressure Increasing Effect of a Newly Synthesized Nitric Oxide Synthase Inhibitor on Septic Shocked Rats[J];GUANGZHOU MEDICAL JOURNAL;1999-04
4 ;氯胺酮对感染性休克大鼠脑组织中热休克蛋白70的影响[J];Contemporary Medicine;2011-09
5 SONG Xuemin,LI Jianguo,WANG Yanlin,ZHOU Qing,DU Zhao-hui,HU ZhengfangDept.of Anesthesiology,Zhongnan Hospital of Wuhan University,Wuhan 430071,China;Protective Effect of Ketamine Against Septic Shock in Rats[J];Medical Journal of Wuhan University;2006-01
6 YIN Gang (Medical School of Yangtze University, Jingzhou 434000,China) WANG Zhi-qiang (Medical College of Three Gorge University,Yichang 443003,China);Studies on effect of Cistanche deserticola Y.C.Ma on the function of liver mitochondria following septic shock[J];Journal of Yangtze University(Natural Science Edition);2005-03
7 FANG Yu,HENG Xin-Hua,WANG Jun(Dept.of Anesthesiology,The 1st Affiliated Hospital of Kunming Medical College,Kunming 650032,China);Modulatory Effects of Ketamine on Mortality in Septic Rats[J];Journal of Kunming Medical College;2006-06
8 FANG Yu,LI Wei,HENG Xin-hua(Dept.of Anesthesiology,The 1st Affiliated Hospital of Kunming Medical College,Kunming 650032,China);Effects of Ketamine on Serum Nitric Oxide and the Second Messengers in Myocardial Tissues of Septic Rats[J];Journal of Kunming Medical College;2007-04
9 WANG Xiao-peng,MU Xiao-jie,WANG Jing-ping,et al.Department of Anesthesiology,Second Hospital,Shanxi Medical University,Taiyuan 030001,China;Effects of metoprolol on expressions of serum cTnI,TNF-α and myocardial NF-κB in septic rats[J];The Journal of Clinical Anesthesiology;2009-03
10 Ge Yuqiang Xu Yuanzhao Liao Lutan Wu ZhaolongDepartment of nephrology, Zhong Shan Hospital, Shanghai Medical University, Shanghai 200032.;Preliminary Creation of the Rat Model of Hypercatabolic Acute Renal Failure[J];Clinical Medical Journal of China;1998-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved