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《Journal of Chengde Medical College》 2001-02
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EFFECT OF YISHENJIANGZHUO DECOCTION ON INTRACEREBRAL ACHE ACTIVITY OF ISCHEMIA REPERFUSION RAT

YUAN Guo hong,GAO Wei juan,MENG Fan xing,et al (Department of Pathophysiology,Chengde Medical College,Hebei Chengde,067000,China)  
Objective:To investigate the effect of YiShenJiangZhuo decoction on intracerebral AchE activity of ischemia reperfusion rat.Methods:After preparing a model of ischemia-reperfusion based on hypotension,we observed the praxiology of rat by using water labyrinth test and AchE activity of hippocampus by colorimetric method.Results:The model rat had distinct disturbances of learning and remembrance the Ache activity increased.The result of learning and remembrance in YiShenJiangZhuo decoction group improved significantly (P0.01)compared with the model rat;And AchE activity in YiShenJiangZhuo decoction group significaitly decreased(P0.05).Conclusion:It is suggested that the YiShenJiangZhuo decoction can improve the learning and remembrance by decreasing the AchE activity of ischemia reperfusion
【Fund】: 河北省科委科研基金资助课题 (课题号 :982 761 87D)
【CateGory Index】: R749.13
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