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《Journal of Chengdu University of Traditional Chinese Medicine》 2006-04
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Laboratory Study on Lithospermum Erythrorhizon on Human Papillomavirus DNA in vitro

LI Jing,LIN Yi,CHEN Wen-na,et al(Department of Dermatology,Shenzhen East Lake Hospital,Shenzhen 518020,China)  
Objective:To screen anti-human papillomavirus(HPV) effective fraction from Lithospermum erythrorhizon.Methods:lithospermum erythrorhizon was extracted with systematic solvents(petroleum benzin,ether,ethyl acetate,n-butanol,ethyl alcohol and distilled water) accordingly.The Fluoresence Quantitative Polymerase Chain Reaction(FQ-PCR) was applied in the vitro pharmacodynamics for the extracts from Lithospermum erythrorhizon.The amplification of HPV-DNA in the lesions of the isolated Condyloma acuminatum.Results:after the water extracts of Lithospermum erythrorhizon was used for HPV-DNA,the PCR amplification showed negative with the minimum effective concertration 0.2g/mL.But the other solvents extracts from Lithospermum erythrorhizon appeared positive.Discussion:the water extracts from Lithospermum erythrorhizon are effective on anti-Human papillomavirus.
【CateGory Index】: R285.5
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