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《JOURNAL OF CHENGDU UNVERSITY OF TARDITIONAL CHINESE MEDICINE》 1997-02
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Effect of Fright to Pregnant Mice on Natural Killer Cell Activity of Filial Generation

Wang Miqu, Huang Jian, Luo Yongzhen, et al Chengdu University of TCM (Chengdu,610075,China)  
In order to research the basic theory of "TCM as fright impairs kidney" and "the kidney being the origin of congenital constitution," experiment was designed as frightening pregnant mice with cat and measuring the natural killer cell activity (NKCA) of its filial generation by improved MTT colorimetric assay. The results Showed that the NKCA of fright group was significantly higher than that of control group(P0.01) and no significant difference lied among the kidney-tonified group,counter group and control group(P0.05).It was suggested that the change of neuroendocrinoimmunological internal enviroment after the pregnant mice being fright-stressed might affect the congenital constitution of the filial generation, causing adaptive cocompensatory abnormal enhancement of its kidney-qi, modulated by Gold-chamber Kidney-qi pill ,which had no significant influence on the NKCA of filial mice from the normal fright-free pregnant mice.
【Fund】: 国家自然科学基金
【CateGory Index】: R22
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