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《Fisheries Science》 2004-06
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Induction of Micronuclei and Nuclear Anomalies in Erythrocytes of Misgurnus anguillicaudatus by Herbicide Acetochlor

XIE Zhi-hao,CAI Ya-fei,CHEN Guo,HUANG Jian-feng,YU Hong-wei (1.Faculty of Life Science and Biotechnology,Ningbo University,Ningbo 315211,China;2.Faculty of Life Science, Anhui Normal University,Wuhu 241000,China)  
Genetic Toxicity of four herbicides:NC-302D(+),Frifluralin,Sofit and 2-ethyl-4chloro sodium hydration,on erythrocytes nucleus of Misgurnus anguillicaudantus were studied by using micronuclei and nuclear anomalies tests.The loach was exposed in various weedicide samples for 24 hours.Smears of blood samples were prepared.The results indicated that four herbicides could all increase genetic index such as the frequencies of micronuclei and nuclear anomalies.Under some concentrations,the frequencies of damage items were different or significantly different in comparison with the control group(P0.05,orP0.01).There were not significant correlation and dose dependant increase between concentrations and micronuclei or nuclear anomalies.The results also showed that four herbicides had significant mutagenic activities on erythrocytes nucleus of Misgurnus anguillicaudatus,and the induction effect of Sofit is higher than the other three herbicides.
【Fund】: 宁波大学校内基金资助项目(0213067)
【CateGory Index】: X174
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