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《Fisheries Science》 2011-11
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Effects of 5-HT on Myeloperoxidase Activity in Haemocytes and Serum of Scallop Chlamys farreri

MA Xue-min,WANG Yi-yan,WANG Yan-jing,SUN Hu-shan(College of Life Science,Ludong University,Yantai 264025,China)  
The activities of myeloperoxidase(MPO) and the content of NO were assayed in haemocytes and serum in scallop Chlamys farreri exposed to different concentrations(0.05,0.5,5 μg/ml) of 5-hydroxytryptamine(5-HT) by biochemical methods.The results showed that there were significantly lower MPO activities in the haemocytes and serum in the scallop exposed to the various levels of 5-HT than that in the control group.The contents of NO in the serum cultured in 5-HT solution at a rate of 0.05 μg/ml were less in the experimental groups than that in the control group without the significant difference.At the concentrations of 5-HT at a rate of 0.5 μg/ml and 5 μg/ml,however,the contents of NO were significantly higher in the experimental groups than that in the control group.In the haemocytes,the contents of NO were significant lower in experimental group than that in the control group,indicating that 5-HT regulated the activity of MPO and the content of MPO and played an important role in immunological defense in the scallop.
【CateGory Index】: S917.4
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