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《China Surfactant Detergent & Cosmetics》 2005-01
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Experimental study of protection animals skin of three wild hamamelidaceae plants extract

XIAO Wei-hong~1,YANG Chun-hua~2,XU Qiu-lin~3,WU Yu-ping~4(1. Jiangxi Key Laboratory of Function Organic Molecules,Nanchang 330013,China;2. Jiangxi Hospital of Skin Diseases,Nanchang 330001,China;3. Nanchang Center of Health & Epidemic Prevention,Nanchang 330001,China;4. Departement of Chemistry Jiangxi Education Institute,Nanchang 330006,China)  
Three kinds of wild plant grown in Jiangxi province,namely Hamamelis mollis,Corylopsis sinensis and Liquidambar formosana were studied for their comprehensive protection effects on the skin of guinea-pigs.Samples of the plants were extracted using ethyl acetate as solvent and the extracts were treated separately by a series of tests,including bacteria (restraining) test,hot plate pain threshold test,anti-inflammation test,skin irritative test and strong UV irradiation test.The experimental results indicate that the extract has restraining effect on the bacteria used in the experiment,can enhance markedly the guinea's pain threshold,can alleviate the inflammation of guinea pig's ears induced by dimethylbenzene remarkablely.There were no skin irritative and allergic reactions under the experimental conditions.Smearing the extraction content could significantly reduce the concentration of malondialdehyde in UV irradiation induced in the guinea's skin.Obviously,the extract from these three plants using ethyl acetate as solvent have good comprehensive protection effects on restraining bacteria,analgesia,anti-inflammation and alleviate free radicals injury of guinea pig's skin resulted from UV irradiation.
【Fund】: 江西省教育厅资助课题(赣教财[2003]97号);; 江西科技师范学院2003年重点资助课题相关研究
【CateGory Index】: TQ658.2
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