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《China Surfactant Detergent & Cosmetics》 2006-01
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Determination of anthraquinone-compound in cosmetics by high performance liquid chromatography

WU Ting~1,WANG Chao~2,LI Jie~1,LI Nan~1(1.College of Science,China Agricultural University,Beijing 100094,China;2.Chinese Academy of Inspection and Quarantine,Beijing 100025,China)  
Three kinds of anthraquinone-compounds(aloin,aloe-emodin and chrysophanol) in cosmetics were simultaneously determined by high performance liquid chromatography(HPLC).The method can be used to evaluate the make up efficacy of cosmetics.The cosmetics were extracted with methanol and the extract was analyzed by HPLC.The 3 components can be separated completely within(11 min).The content of each component shows good linearity with the corresponding HPLC peak area within the range of(1 μg/mL)~(250 μg/mL)(R(0.999 7)).As the additive concentration is within(0.5 μg/mL)~(5.0 μg/mL),the recovery achieves(92.0%)~(102.5%).The relative standard deviation was less than(2.1%).The detection limit(S/N=3) achieves(0.516 0 μg/mL) for aloin,(0.086 4 μg/mL) for aloe-emodin and(0.101 6 μg/mL) for(chrysophanol.)
【CateGory Index】: TQ658
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