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《Chinese Journal of Neuro-Oncology》 2004-03
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Chemotherapy for Brain Metastases

Wen Zhang Da-tong Chu Department of Medical Oncology,Cancer Hospital & Institude,CAMS & PUMC,Beijing 100021,P.R.China  
Brain metastases are the most common intracranial tumor of adults,and the incidence of brain metastases is increasing.Because the majority of cytotoxic agents seem to be unable to penetrate the blood-brain barrier,the role of chemotherapy in the treatment of brain metastases remains controversial.In the fact,the blood-brain barrier is disrupted in brain metastases,and does not limit the response to chemotherapy. The most important factor affecting the response to cytotoxic agents is the chemosensitivity of different tumors.New- er drugs are now on study:temozolomide seem to be particularly promising(alone or in association with other drugs)in the treatment of various brain metastases.
【CateGory Index】: R739.4
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【Citations】
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【Co-citations】
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1 LI Qing1, FENG Feng yi1, HAN Jun2, SUI Guang jie3, ZHU Yan guang4, ZHANG Yang5, ZHANG Zhen hua6, LI Li7, WANG Ping hui8, ZHOU Mei zhen9, ZHANG Ying chao101. Cancer Hospital,Chinese Academy of Medical Sciences,Beijing 100021,P.R.China2. Shanxi Provincial Cancer Hospital,Xian 710061,P.R.China 3. Heilongjiang Provincial Cancer Hospital,Harbin 150040,P.R.China 4. Xijing Hospital of The Fourth Military Medical University,Xian 710032,P.R.China 5. The Second Clinical College of Dalian Medical University,Dalian 110121,P.R.China6. The First Affiliated Hospital of Xian Medical University,Xian 710061,P.R.China 7. The Affiliated Hospital of Shandong Medical University,Jinan 250012,P.R.China8. Cancer Hospital of Hunan Province,Changsha 410006,P.R.China9. Beijing Hospital,Beijing 100078,P.R.China 10. Cancer Hospital of Sichuan Province,Chengdu 610041,P.R.China;Phase Ⅲ Clinical Study of a New Anticancer Drug Atofluding[J];Chinese Journal of Cancer;2002-12
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5 Xiu-ping Zhang1, Jian Li1, Lai-ji Huang1, Zhan-shu Zhang2 1. Department of Radiation Oncology, Cancer Hospital, Guangzhou Medical Collage, Guangzhou, Guangdong 510095, P.R. China; 2. Cancer Center, Guangdong General Team Hospital of Armed Police, Shenzhen 518029, P.R.China;Preliminary Results of Erlotinib Concomitant with Radiation Therapy for Non-small Cell Lung Cancer Patients with Multiple Brain Metastases[J];Chinese Journal of Neuro-Oncology;2007-03
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