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《Chinese Journal of Neuro-Oncology》 2004-03
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Progress in the Study of Penetration into Blood-brain Barrier of New Anti-lung Cancer Drugs

Qun-Ying Yang Guang-Chuan Xu Li-Kun Chen Department of medical oncology,,Cancer Cencer,Sun Yat-sen University,Guanzhou 510060,P.R.China  
The brain metastases of lung cancer are increasing.The blood-brain harrier(BBB)was consid- ered to be the major hindrance to the successful chemotherapeutic treatment of brain metastases.However,the re- cent studies have demonstrated a break down of the BBB in large area of the tumor vasculature.In this paper,the penetration of new anti-lung cancer drugs into BBB and the use of chemotherapy in brain metastases from lung can- cer are reviewed.With the development of new anti-lung cancer drugs,chemotherapy should become an indispens- able part of treatment for brain metastases of lung cancer.
【CateGory Index】: R96
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