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《Chinese Journal of Neuro-Oncology》 2006-03
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Acute Cerebral Herniation in Plateau Area due to Intracranial Tumors:Analysis of 11 Cases

Zhi Pu, Yixi A-Wang Department of Neurosurgery, Tibet People's Hospital, Lhasa,Tibet Autonomous Region 850000, P.R. China  
BACKGROUND OBJECTIVE: Acute cerebral herniation in plateau area due to brain tumor could have distinctive clinical manifestation. In this article, the clinical characteristic, causative factors, laboratory examinations, treatments and prognosis of acute brain herniation due to intracranial tumors in plateau area were analysed. METHODS: Eleven patients with acute brain herniation due to intracranial tumors who received operation in our department from 1999 to 2005 were reviewed. In this group, 10 cases were plain residents, among which 8 cases experienced sudden coming into plateau area and 2 cases had temporally lived in the plateau area for 3 months. Another case was local resident, who developed acute brain herniation when descending from 4500 to 3700 metres altitude.The age of the patients ranged from 31 to 52 years old (average 38.9 years old). RESULT: All the patients received CT scan examination and 3 cases did MRI scan. The tumors' diameter ranged from 3 to 6 cm. The craniotomy was done urgently in 8 cases to remove the tumor. There were 3 cases whom firstly received adequate medical therapy including anti-convulsants, dehydration and symptomatic treatments, then surgery was done in scheduled time. There were no surgical mortality. All the removed tumors were pathologically diagnosed meningiomas. CONCLUSIONS: Headaches, vomiting, epilepsy and coma are the most frequent clinical symptoms in the patients with acute brain hernia due to brain tumors in plateau area, and sudden coming into plateau is the primary causative factor. If there was no improvement for consciousness level after proper medical therapy, craniotomy should be performed immediately.
【CateGory Index】: R739.41
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