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《Chinese Journal of Neuromedicine》 2005-04
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TCD flow pattern at the last stage of intracranial hypertension in rabbits

WAN Jing-wen, WU Gang, LIN Jian-dong. Department of Neurology, First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China  
Objective To observe the changes of transcranial Doppler flow patterns at the last stage of intracranial hypertension before rabbits' death in order to research the role of transcranial Doppler in the diagnosis of brain death. Methods The animal models with acute intracranial hypertension was established in the means of inserting epidurally the balloon inflated with water. Intracranial pressure and blood flow velocity were measured with transcranial Doppler. Results At the last stage of intracranial hypertension Doppler sonograms showed three characteristic flow patterns in the following sequence: retrograde diastolic flow, small systolic triangular flow, no flow. Conclusion According to three characteristic flow patterns, brain death can be diagnosed reliably.
【Fund】: 福建省教育厅立项课题(JA01071)
【CateGory Index】: R445.1
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