Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Neuromedicine》 2005-05
Add to Favorite Get Latest Update

Clinical evaluation of Oxiracetam in the treatment of craniocerebral trauma

SHU Kai, XI Gui-fa, NIU Hong-quan, DONG Zhen, YU Jia-sheng, LEI Ting, LI Ling. Department of Neurosurgery, Tongji Hospital, Tongji Medical College, H uazhong University of Science and Technology, Wuhan 430030, China  
Objective To study and evaluate the effect of oxiracetam on c raniocerebral trauma. Methods 120 patients with medial craniocerebral trauma were randomized by double blindness into 2 groups using oxiracetam and positive drug piracetam respectively in the experimental group and the control group. MM SE, GCS, GOS and self-consciousness symptom scale were employed to evaluate the effect. The subjects in the experimental group and the control were orally admin istrated with oxiracetam and piracetam respectively, 2.4g per day, 30 d as one c ourse. Results In the experimental group, significant curative effect occu rred in 20 cases (33.3%), curative effect in 30 cases (50.0%), the total effecti ve rate reaching 83.3%. Compared to the control group, the difference was signif icant (P0.05). Conclusion Oxiracetam, a kind of safe and effective nootropi cs, can treat nervous dysfunction induced by craniocerebral trauma, accelerate f unctional rehabilitation and improve the quality of life of patients, so in clin ic it can be used extensively.
【CateGory Index】: R651.15
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 Wang Liwen,Zhao Zhigang(Affiliated Beijing Tiantan Hospital,Capital Medical University,Beijing 100050,China);Zhong Guo, Zhu Chuanjun(School of Pharmaceutical Science,Peking University);Analysis on Drug Use of Craniopharyngioma in Our Hospital from 2004 to 2008[J];China Pharmacist;2009-07
【Citations】
Chinese Journal Full-text Database 1 Hits
1 Hai li bi nu er, WANG Yin hua, ZHAO Fa guo (Department of Neurology, The First Hospital of Peking University, BEIJING 100034, China);Randomized double-blind controlled study of oxiracetam vs piracetam in treatment of vascular dementia[J];Chinese Journal of New Drugs and Clinical Remedies;2003-11
【Co-citations】
Chinese Journal Full-text Database 9 Hits
1 FANG Bo,CAI Yun-hong,YUAN Peng,et al.(1.Department of Neurosurgery;2.Department of Neurology,Emergency Medical Center of Chongqing,Chongqing 400014,China);Clinical study of treating impediment of anamnesis and aptitude in the convalescent patients with severe head injury by oxiracetam[J];Chongqing Medical Journal;2005-11
2 ZHU Ji (Department of Neurosurgery, The First Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 400016, China);Clinical study of oxiracetam for mild or medium brain injury[J];Acta Academiae Medicinae Militaris Tertiae;2006-10
3 CHU Chue,CAI Yun-hong(Department of Neurology,Chongqing Emergency Medicine Center.Chongqing 400014,China);The safety and efficacy of oxiracetam in patients with Vascular Dementia[J];Laser Journal;2005-02
4 YAO Ge,CHENG Jie,WANG Xiao-rong,LIU Zheng-guo Department of Neurology,Xinhua Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200092,China;Clinical study of oxiracetam for treatment of Alzheimer's disease[J];Geriatrics & Health Care;2007-05
5 XU Hong-hua.Affiliated Gulou Hospital of Nanjing University Medicine College,Nanjing,Jiangsu 210008,China;The comparison study of nicergolent and piracetam in treatment with vascular dementia.[J];Sichuan Medical Journal;2009-09
6 WANG Shu-zhen~(1*) CHI Zhao-fu~1 MA Lin~1 ZHANG Yong~2 DI Qing~3 HAN Zhao~4 YU Hao~5 HAN Ting~6 (1.Department of Neurology,Qilu Hospital of Shandong University,Ji-nan SHANDONG 250012,China:2.Department of Neurology,Shandong Provincial Hospital,Ji-nan SHANDONG 250021,China;3.Department of Brain Hospital of Nanjing Medical University,Nanjing JIANGSU 210029,China;4.The First Affiliated Hospital of Wenzhou Medical College,Wenzhou ZHEJIANG 325000,China;5.Department of Epidemiology and Biostatistics School of Public Health,Nanjing Medical University,Nanjing JIANGSU 210029,China;6.Shijiazhuang Pharmaceutical Group Ouyi Pharmaceutical Company,Shijiazhuang HEBEI 050051,China);A randomized double-blind controlled multicenter study with oxiracetam for injection in treatment of organic brain syndrome[J];Chinese Journal of New Drugs and Clinical Remedies;2007-04
7 ZHANG Kai, HOU Ying-zhi, ZHANG Jian-guo, et al . Department of Neurosurgery, Beijing Tiantan Hospital, Beijing 100050, China;Clinical Study of Curative Effect of Oxiracetam Injection on Brain Injury[J];Chinese Journal of Clinical Neurosurgery;2005-02
8 HUA Jin-bao (Zhejiang Province Anji the Third People's Hospital,313301,China);Clinical observation on oxiracetam's effects on rehsbitation of cognitive function in patients of hypertensive cerebral hemorrhage[J];Chinese Journal of Hospital Pharmacy;2008-14
9 GUO Xiaofeng(The Peoples' Hospital of Xiangtan County,Hunan Province,Xiangtan 411100,China);Clinical study of curative effect of oxiracetam injection on medium or serious brain injury[J];China Modern Medicine;2009-19
【Co-references】
Chinese Journal Full-text Database 9 Hits
1 JIANG Feng, HUA Xuming, ZHANG Wenchuan, WAN Liang, LIU Ming, WU Weilie Department of Neurosurgery, Xinhua Hospital, Shanghai Second Medical University, Shanghai 200092, China;Clinical analysis of unilateral oculomotor palsy[J];Chinese Journal of Neuromedicine;2004-01
2 HU Jinqing, LIN Dong, SHEN Jiankang, ZHAO Weiguo Department of Neurosurgery, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China;Recovery of the oculomotor nerve palsy after posterior communicating artery aneurysmal embolization with Guglielmi detachable coil[J];Chinese Journal of Neuromedicine;2004-04
3 ZHENG Youzhi, WAN Daqing, SHEN Yiqin, CHEN Yejun, CAI Xuejian ,LIU Bin.Anesthesiology Department,The 101 Hospital of PLA, Wuxi 214044, China;Efficacy of continuous papaverine infusion into the subarachnoid cavity on preventing cerebral vasospasm in patients after aneurism operation[J];Journal of Emergency Medicine;2005-03
4 LIU Xiao-Yong ZHANG Shi-Ming WANG Zhong ZHOU You-Xin CUI Gang LI Xiang-Dong ZHOU Dai Department of Neurosurgery,The First Affiliated Hospital of Soochow University,Suzhou 215006,China;Analysis of Factors Effecting Prognosis of Ruptured Intracranial Aneurysms[J];Chinese Journal of Clinical Neurosciences;2008-06
5 LIU Ning-tao1,HUANG Xiao-song1,LI Shi-ting2,PAN Qing-gang1,WANG Fei1,GUAN Yu-hang1 (1.Dept.of Neurosurgery,Tongji Hospital,Tongji University,Shanghai 200065,China;2.Dept.of Neurosurgery,Xinhua Hospital,Jiaotong University,Shanghai 200092,China);Study on nerve growth factor in repairing oculomotor nerve injury in rats[J];Journal of Tongji University(Medical Science);2007-05
6 WANG Shu-zhen~(1*) CHI Zhao-fu~1 MA Lin~1 ZHANG Yong~2 DI Qing~3 HAN Zhao~4 YU Hao~5 HAN Ting~6 (1.Department of Neurology,Qilu Hospital of Shandong University,Ji-nan SHANDONG 250012,China:2.Department of Neurology,Shandong Provincial Hospital,Ji-nan SHANDONG 250021,China;3.Department of Brain Hospital of Nanjing Medical University,Nanjing JIANGSU 210029,China;4.The First Affiliated Hospital of Wenzhou Medical College,Wenzhou ZHEJIANG 325000,China;5.Department of Epidemiology and Biostatistics School of Public Health,Nanjing Medical University,Nanjing JIANGSU 210029,China;6.Shijiazhuang Pharmaceutical Group Ouyi Pharmaceutical Company,Shijiazhuang HEBEI 050051,China);A randomized double-blind controlled multicenter study with oxiracetam for injection in treatment of organic brain syndrome[J];Chinese Journal of New Drugs and Clinical Remedies;2007-04
7 Chen Duo Dong Xinming Guan Junhong et al Department of Neurosurgery, the 2nd Affiliated Hospital of China Medical University, Shenyang;Craniopharyngioma: An Analysis of Microsurgery and Factors Influencing Prognosis[J];Chinese Journal of Clinical Oncology;2007-05
8 WANG Zhi-gang DING Xuan QU Chun-cheng JI Yong ZHANG Ji-qing LI Tao WANG Cheng-wei PAN Shun Department of Neurosurgery,The Second Hospital,Shandong University,Jinan 250033,China;Outcomes of surgical versus endovascular treatment for ruptured cerebral aneurysms[J];Chinese Journal of Neurosurgery;2007-11
9 ZHAO Xin-li,ZHOU Guo-sheng,ZHOU Wen-ke,et al(Department of Neurosurgery,the First Affiliated Hospital of Xinxiang Medical University,Weihui 453100,Henan Province,China);Experience of microsurgical treatment of posterior communicating artery aneurysms and influence of resecting the sac on the recovery of oculomotor nerve palsy[J];Medical Information(Section of Operative Surgery);2007-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved