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《Journal of Materials Science and Engineering》 2004-05
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Preparation and Characterization of Magnetic Chitosan Microspheres for the Carriers of Radionuclides in Therapy

JIANG Wei 1, LI Feng-sheng 1, YANG Yi, LIU Hong-ying 1, CHU Jiang-jun 2 (1. National Special Superfine Powder Engineering Research Center, Nanjing University of Sci. & Tech., Nanjing 210094, China; 2.Institute of Tumor Prevention and Cure, Wuxi, China)  
In this paper, magnetic chitosan microspheres which can load radionuclides were prepared by the suspension cross-linking technique. The results demonstrated that the concentration of chitosan solution, Fe 3O 4/chitosan ratio and stirring rate of the suspension medium were the most effective parameters for the size/size distribution, morphology and magnetism of magnetic chitosan microspheres. Furtherly, the best preparation circuit is optimized. Finally, the size, size distribution, morphology and magnetism were studied by different instruments.
【Fund】: 国家自然科学基金资助项目 (50 30 60 0 8) ;; 江苏省自然科学基金资助项目(BK2 0 0 342 1 )
【CateGory Index】: TQ460.4
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