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《Journal of Chongqing University of Science and Technology(Natural Sciences Edition)》 2006-04
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The Experimental Research on Hypnogenetic Effects of Gypenosides

XU Lu DONG Zhi HUANG Yan(Chongqing University of Medical Sciences,Chongqing 400016)  
Objective: To investigate the hypnogenetic effects of gypenosides on mice models.Methods: The mice were given all the drugs by ig to determine the times of free movement.The effect of gypenosides with Sodium pentobarbital(subthreshold doses and superthreshold doses) in mice were determined.Results: High dose group gypenosides could decrease the times of spontaneous motion at 40 min(p0.01).High dose group could prolong the sleeping time with superthreshold doses Sodium pentobarbital(p0.01).High dose group could increase the number of sleeping mice with subthreshold doses(p0.01.Conclusion:Gypenosides has effects on hypnosis and sedation.
【CateGory Index】: R285
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