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《Chongqing Medical Journal》 2004-01
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The correlation between endothelins-1 and echocardiogram parameters of cardiac function in heart failure

XIAO Hua,QIN Shu (Department of Cardiology,the First Affiliated Hospital,Chonqging University of Medical Sciences,Chonqging 400016,China)  
Objectives To discuss the significance of endothelins 1(ET 1) in the progress of heart failure.Methods The plasma levels of ET 1 were tested by specific radio immunoassay and the echocardiogram parameters of cardiac function were obtained in different grade patients with heart failure.Results The plasma levels of ET 1 elevated with the worsening of heart failure (NYHA Classification).The plasma levels of ET 1 were negatively correlated with left ventricle ejection fraction (LVEF)and fraction shortening (ΔD%) and positively correlated with left ventricl end systolie volumeml(LVSd) and left ventricle end diastolic volumeml (LVDd).Conclusion In progressing of heart failure,ET 1 has a close correlation with the cardiac function and echocardiogram parameters of cardiac function in heart failure.
【CateGory Index】: R541.6
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