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《Chongqing Medicine》 2007-08
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A study on anti-aging action of Potentilla anserina Lextract

XIE Xue-yuan,WANG Qiang(Department of Pharmacy,Naval General Hospital,Beijing 100037,China)  
Objective To investigate the effect of Potentilla anserina extract(JME) on aged mice induced by D-galactose.Methods The aged mice were induced by D-galactose.Meanwhile,they were filled with three doses of JME.Then,the ability of memory,the activities of antioxidase in different tissue,the contents of MDA in brain,liver and serum were observed after 6 weeks.Results Compared with the model group,JME could significantly improve the ability of memory,markedly strengthen the activities of SOD in brain and liver,GSH-Px in liver and blood and Na+-K+-ATPase in brain,decrease the activities of MAO in brain and contents of MDA in brain,liver and serum.Conclusion JME possesses the anti-senility effect probably by improving free radical metabolism.
【CateGory Index】: R285.5
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