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《Chongqing Medicine》 2007-11
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Initial clinical research of biomimetic and supportive n-HA/PA66 composites for structural reconstruction of vertebral body in spine

JIANG Dian-ming,QUAN Zheng-xue,OU Yun-sheng,et al.(Department of Orthopaedics,First Affiliated Hospital,Chongqing University of Medical Sciences,Spinal Surgical Center of Chongqing,Chongqing 400016,China)  
Objective To study the clinical effects of the biomimetic and supportive n-HA/PA66 composites for the structural reconstruction and height restoring of vertebral body in the thoracolumbar spine.Methods Thirty-six patients received operation to reconstruct the spinal vertebral structure with the biomimetic and supportive n-HA/PA66 composites from anterior approach because of the vertebral deficit.There were 32 cases of vertebral bursting fracture,2 cases of spontaneous discitis and 2 cases of vertebral tumor in this series.Results The period of follow-up lasted 8 months,ranging from 6 to 21 months.The implant was healed after 3 or 4 months postoperatively.The reconstructive height of vertebra was maintained.The neural symptoms were improved in different degree.Conclusion The biomimetic and supportive n-HA/PA66 composites can effectively restore the height and structure of vertebra,and can be fused with vertebral body to reconstruct spinal structural stability effectively.And they can be extensively used in clinic.
【Fund】: 国家高新技术研究发展“863”计划资助项目(2002AA326020)
【CateGory Index】: R318.08;R687.3
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