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《Chongqing Medicine》 2007-13
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Expression and clinical significance of MMP-9,VEGF in renal cell carcinoma

ZHANG Yao,WU Xiao-hou,SUN Xiang-yu,et al.(1.Department of Urologic Surgery,People's Hospital of Suining City,Suining,Sichuan 629000,China;2.Department of Urology,First Affiliated Hospital,Chongqing University of Medical Sciences,Chongqing 400016,China)  
Objective To study the expressions of matrix metalloproteinase-9(MMP-9),vascular endothelial growth factor(VEGF) and their correlation with angiogenesis and biological behaviour in renal cell carcinoma(RCC).Methods The expressions of MMP-9,VEGF and CD34 were detected by means of immunohistochemistry in 78 cases of RCC.Results The positive expression rate of MMP-9 was 87% in the high staging group and 50% in the low staging group,the statistical significance existed between the two groups(P0.01);the MVD was 140.86±24.87 in both positive expressions of MMP-9 and VEGF,was higher than that in the single positive ones(99.3±47.97)(P0.01)and the both negative ones(80.16±33.83)(P0.000 1).The expression of MMP-9 correlated with VEGF in renal cell carcinoma(r=0.409 66,P0.01).Conclusion MMP-9 and VEGF may serve as biological predictor for tumor metastatic potential in renal cell carcinoma.
【CateGory Index】: R737.11
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2 LI Bin1,CHEN Wu-ke2,CHEN Peng3,et al.(1.Department of Tumor,Affiliated Hospital of Xi′an Medical College,Xi′an 710077,China;2.Department of Tumor Surgery,First Affiliated Hospital of Xi′an Traffic University,Xi′an 710061,China;3.Department of Biochemistry,Xi′an Medical College,Xi′an 710021,China);Clinic pathological study of metastasis-associated protein1 (MTA1),Matrix Metalloproteinase-9(MMP-9) expression in breast cancer[J];Chongqing Medicine;2010-12
3 JIANG Cui-ping,et al (Department of Urology,the First Affiliated Hospital,Chongqing Medical University);The differential expression of VEGF165b in the renal cell carcinoma and normal renal tissues and its clinical significance[J];Journal of Chongqing Medical University;2009-03
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Chinese Journal Full-text Database 9 Hits
1 MOU Jiang-hong,YAN Xiao-chu,XIAO Hua-liang,et al.(1.Department of Pathology,Daping Hospital,Chongqing 400042;2.Institute of Pathology,Southwest Hospital,the Third Military Medical University,Chongqing 400038,China);High expression of VEGF-C and VEGFR-3 mRNA and its implication in colorectal cancer[J];Chongqing Medicine;2006-03
2 HE Xing-xiang1, LI Xiao-yu2, GUO Hai-bo2, HUANG Shi-zhang2, GAO Fu-yuan3(1.the Clinical Medical College of Guangdong Pharmaceutical University, Guangzhou 510310; 2.the Second Affiliated Hospital of GuangzhouMedical College, Guangzhou 510260; 3.Medical school of Hubei Qianjiang, Qianjiang 433100, China);Increased expression of macrophage migration Inhibitory factor in epithelial and serum in patients with colorectal carcinoma[J];Basic & Clinical Medicine;2008-08
3 ZHU Haizhou (Jining Medicial College,Shandong Jining);The Expression of eNOS VEGF and ET-1 Protein in Vibrated Male Rabbits[J];Journal of Jining Medical College;2008-02
4 DUAN Wen-kai,GUO Fu-jun(First Affiliated Hospital,Henan University of Science and Technology,Luoyang 471003,China);Expression of Matrixmetalloproteinases-9 in Salivary Mucoepidermoid Carcinoma[J];Journal of Henan University of Science & Technology(Medical Science);2008-01
5 LIANG Lu-nan,ZHU Hai-zhou,XIAO Lin(Affiliated Hospital of Jining Medical College,Ji Ning 272019,China);The expression of VEGF,Flt-1 and MVD in benign prostatic hyperplasia[J];Journal of Taishan Medical College;2007-08
6 HAN Bo,GAO ChengDepartment of Surgery,the Second Hospital of Qingdao Medical College,Qingdao 266042,China;The expression of E-cadhiren,matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in colorectal cancer:relationship with biological behavior and the patient survival[J];Chinese Journal of Gastroenterology and Hepatology;2008-04
7 HAN Bo,ZHANG Xu.The Second Affiliated Hospital,Qingdao Medical College,Qingdao 266042,China;Association among the expressions of MMP-9,TIMP-1 and invasion,metastasis and prognosis in colorectal carcinoma[J];Chinese Medical of Factory and Mine;2007-04
8 Yang Fu Jiang Zhi Hua Yang Jin Qun Hu Cancer Institute, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China;Recurrence or metastasis of HCC:predictors,early detection and experimental antiangiogenic therapy[J];世界胃肠病学杂志(英文版);2000-01
9 ZHENG Jin-hua,SUN Jiang-bin,WU Mei,et al.(China-Japan Union Hospital of Jilin University,Changchun 130033,China);The expression rates and the correlation of survivin、MMP-2、MMP-9 of colorectal carcinoma[J];Chinese Journal of Laboratory Diagnosis;2009-10
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1 Jiang Zhong Qing, Zhu Feng Chuan, Qu Jun Ying, Zheng Xiu, You Cai LingDepartment of Obstetrics andGynecology,The Affiliated FirstHospital,Fujian Medical University,Fuzhou,Fujian,350005,P.R.China;Relationship between Expression of Matrix Metalloproteinase (MMP-9)and Tumor Angiogenesis,Cancer Cell Proliferation,Invasion,and Metastasis in Invasive Carcinoma of Cervix[J];Chinese Journal of Cancer;2003-02
2 MEI Tong-hua 1, LUO Bin 1, MA Ying 2 ( 1Department of Respiratory Disease, 2Department of Pathology, Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 400010, China);Expressions of MMP-2, MMP-7 and TIMP-2 in lung carcinoma and their significance[J];Acta Academiae Medicinae Militaris Tertiae;2004-16
3 LIANG Jun, LIU Mingqiu, XIE Mei, LIU Xuan. Department of Nuclear Medicine, Wuhan University People Hospital, Wuhan, Hubei 430060, P.R.China;Expressions of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 and their correlation with metastasis and prognosis in lung cancer[J];Chinese Journal of Lung Cancer;2003-01
4 Gao Xia, Diao Luming, Li Heng, et al Dept. of Pathology, School of Medicine, Wuhan University,Wuhan 430071,China;Expression of c-Met Protein in Non-small Cell Lung Carcinoma and Its Relationship with Tumor Cell Proliferation and Angiogenesis[J];Journal of Hubei Medical University;2005-03
5 XUE Yang,ZHOU Qing-hua,ZHANG Shang-fu,et al.(1.The Department of Cardiothoracic Surgery,Sichuan Provincial People's Hospital,Chengdu,Sichuan 610072,China;2.The Department of Cardiothoracic Surgery,Tianjin Medical University General Hospital,Tianjin 300052,China;3.West China Hospital,Chengdu Sichuan 610041,China);A Study on the Relationship Between Expression of MMP-2,MMP-9 and Metastasis and Prognosis in Patients with Lung Cancer[J];West China Medical Journal;2008-02
6 LI Meng-quan,LI Jing-ruo,BAO Jun-tao,SU Jing,LI Jian-zhang(The First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052,R.P.China);Expression of MTA1 pretein in breast cancer and its significance[J];Shandong Medical Journal;2007-15
7 WU Xiaohou, et al (Department of Urology, College of Clinical Medicine, Chongqing Medical University);An study of expression of vascular endothelial growth factor in urinary cytology in transitional cell bladder carcinoma[J];Acta Universitatis Scientiae Medicinae;2002-01
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 Yang Chunrong1, 2, Zhang Hui1, 2, Huang Wei1, 2, Liu Qiong1,2 (1Chongqing Research Centre of Molecular Medicine and Cancer, 2Department of Pathology, College of Basic Medical Sciences, Chongqing Medical University, Chongqing, 400016, China);Combination of pyrrolidine dithiocarbamate and paclitaxel suppresses proliferation and invasion of MDA-MB-231 cells[J];Acta Academiae Medicinae Militaris Tertiae;2010-06
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 WU Chen qiu,CHEN Wen, ZHANG Qiao, et al.(Department of Health Toxicology, School of Public Health, Sun Yan sen University of Medical Scienes, Guangdong Guangzhou 510089, China);Expression of proliferating cell nuclear antigen during the development of rat colon cancer induced by 1,2 dimethylhydrazine[J];China Oncology;2000-06
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