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《Chongqing Medicine》 2007-17
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Minocycline influences on serum SOD,MDA in rats with focal cerebral ischemia-reperfusion

CAI Zhi-you,YU Chang-yin,ZHANG Jun,et al.(1.Department of Neurology,First Affiliated Hospital,Chongqing University of Medical Sciences,Chongqing 400016,China;2.Department of Neurology,Affiliated Hospital,Zunyi Medical College,Zunyi,Guizhou 563003,China)  
Objective To observe the influence of minocycline on serum SOD,MDA of focal cerebral ischemia-reperfusion injury in Wistar rats.Methods Wistar rats were randomly divided into: normal groups(N),ischemia-reperfusion groups(IR),sham-operation groups(NS),minocycline groups(M),minocycline treatment groups(MT) and minocycline preconditioning groups(MP).Taking the cerebral tissue after killing the rats by injecting high-dose hydrate chloride.The serum thickness of SOD and MDA was measured by the chemical colorimetry,the pathological feature of cerebral tissue was detected by HE staining.Results The serum thickness of SOD in MP and MT groups was significantly higher than that in IR(P0.01).The serum thickness of MDA in MP and MT groups was significantly higher than that in IR(P0.01).Conclusion Minocycline can increase the serum thickness of SOD and decrease that of MDA,it can protect neural function by enhancing clearance of free radical.
【CateGory Index】: R96
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【References】
Chinese Journal Full-text Database 7 Hits
1 HUANG Cheng-hong,CAI Zhi-you,ZENG Ling-qiong,et al.(Neurology Department of the First Affiliated Hospital of Chongqing Medical University,Chongqing Key Labarotry of Neurology,Chongqing 400016,China);Upregulation of VEGF and downregulation of IL-1β,TNF-α in vascular dementia rats by minocycline[J];Chongqing Medicine;2008-07
2 CHENG Ze-pei1,CAI Zhi-you2,LIU Wei3,et al.(1.Department of Neurology Chongqing Third People′s Hospital,Chongqing 400014,China;2.Department of Neurology,First Affiliated Hospital,Chongqing University of Medical Sciences,Chongqing 400016,China;3.Department of Emergency,Chongqing Third People′s Hospital,Chongqing 400014,China);Pathogenesis of oxidative stress and activated hyperglycaemia in cerebral hemorrhage[J];Chongqing Medicine;2008-13
3 HE Yong-li1,CAI Zhi-you2,YAN Yong2(1.Chongqing Occupation Disease Prevention and Treatment Center,Chongqing 400060,China;2.Department of Neurology,First Affiliated Hospital,Chongqing University of Medical Sciences,Chongqing 400016,China);Relationship between serum level of IL-18,IFN-γ and oxidative stress in acute spontaneuse cerebral hemorrhage[J];Chongqing Medicine;2008-24
4 LU Wei-hua,ZENG Xian-mei,SHAO Su-hua,et al.(Department of Emergency,Wuhan General Hospital of PLA Guangzhou Military Command,Wuhan 430070,China);Protective effect of HO-1 on myocardial ischemia/reperfusion injury in rats[J];Chongqing Medicine;2009-11
5 DONG Min,XI Gang-ming,ZHANG Zheng-hong (Department of Neurology,The Affiliated Renmin Hospital of Yunyang Medical College,Shiyan,Hubei 442000,China);Neuropretection of PEP-1-SOD1 fusion protein against cerebral infarction in murine hippocampal region[J];Chongqing Medicine;2010-12
6 FAN Ye-hong,SHEN Li-ming(Nursing College of Heilongjiang Province,Harbin 150086,CHINA);Protective Effect of SQHJ on Experiment Cerebral Ischemia Rats[J];Heilongjiang Medical Journal;2011-06
7 BAO Xue-ying1 QI Xin1 HU Yuan1 LIU Yu-xiang1 XIE Jing1 QU Ji-bing2(1Department of Neurology,The 208th Hospital of PLA,Jilin Changchun 130062;2Department of Pharmacology,School of Basic Medicine,Jilin University,Jilin Changchun 130021);Neuroprotection of Total Flavones of Bidens Bipinnata L.on Brain Damage Following Experimental Intracerebral Hemorrhage in Rats[J];Chinese Journal of Pharmacovigilance;2010-12
【Citations】
Chinese Journal Full-text Database 3 Hits
1 LIU Lei,ZHAO Shi-fu,SONG Chuan,et al. (1.Department of Neurology,324 Hospital of PLA,Chongqing 400020,China; 2.Department of Neurology,Xingqiao Hosptial,the Third Military Medical University,Chongqing 400037,China);Inhibition of hyperbaric oxygen on iNOS expression of gerbil to alleviate ischemic nueronal apoptosis[J];Chongqing Medical Journal;2005-03
2 GONG Biao,LI Chang-qing,HUANG Jian(1.TCM College Chongqing University of Medical Sciences,Chongqing 400050,China;2.Second Hospital Affiliated to Chongqing University of Medical Sciences,Chongqing 400010,China);Modification of suture methods for rat model of focal cerebral ischemia/reperfusion[J];Chongqing Medicine;2006-04
3 LI Jian-sheng~ * , LIU Jing-xia, YU Hai-bin, WANG Dong.~ * Department of Geriatrics, Henan College of Traditional Chinese Medicine, Zhengzhou 450003, Henan, China;Establishment and evaluation of reproduction of middle cerebral artery occlusion to produce cerebral ischemia with autologous blood clot and nylon thread in rat[J];Chinese Critical Care Medicine;2006-05
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LI JIAN-YUAN,ZHANG YA-ZHUO,YAO WEI-CHENG,et al(Department of Neurosurgery,The Affiliated Hospital of Qingdao University Medical College,Qingdao 266003,China);;A COMPARISON OF TWO METHODS IN MAKING ISCHEMIA-REPERFUSION MODEL OF MIDDLE CEREBRAL ARTERY IN RATS[J];Acta Academiae Medicinae Qingdao Universitatis;2008-05
2 LI Jian-sheng1,LIU Jing-xia2,WANG Dong3,LIANG Sheng-wang1,LIU Ke1,GUO Xiao-yan1,SUN Jie1,LI Ning1,SU Jing1(1Geriatrics Institute of Henan College of TCM,Zhengzhou 450008,China;2TCM School of Ningxia Medical University,Yinchuan 750004,China;3Children,s hospital of Femme and Child Care Centre of Luoyang City in Henan Province,Luoyang 471000,China);Study of Rhubarb aglycone on time window of thrombolysis therapy through artery in rats with thrombus-occluded cerebral ischemia[J];China Journal of Traditional Chinese Medicine and Pharmacy;2011-09
3 ZHENG Xiao-ying,ZHAO Shu-min,CHEN Meng,et al (Chengde Medical College,Heibei Chengde 067000,China);CHANGES OF SOD AND MDA IN BRAIN OF FOCAL CEREBRAL ISCHEMIA-REPERFUSION MODEL RATS[J];Journal of Chengde Medical College;2009-01
4 LUO Xiao-ming,CHEN Xin-fu,QIAN Cheng,et al.(Department of Neurosurgery,161 Central Hospital of PLA,Wuhan,Hubei 430010,China);Changes and effect of GSK-3β and Bax on EPO intervention on rat brain injury suffered from ischemia-reperfusion[J];Chongqing Medicine;2007-16
5 DIAO Yu-jing1,ZHAO Ming2,JIANG Peng2,et al.(1.Clinical Medical College;2.Department of Anesthesiology,Affiliated Hospital;3.Center Lab of Affiliated Hospital,Jiangshu University,Zhenjiang,Jiangshu 212001,China);Effect of Shenmai injection on the changes of Platelet endothedial cell adhesion molecule-1(PECAM-1) on myocardial ischemia/reperfusion injury in rats[J];Chongqing Medicine;2010-15
6 Hu Yuying,Liu Tai,Zhang Qingping,Yi Ming,He Qianchao,Liang Ni(Department of Neurology,First Affiliated Hospital of Guangxi Medical College,Nanning,Guangxi 530023,China);The effects of Jiaotai pill on vascular dementia rat model of learning and memory ability and brain cholinergic mechanisms[J];Chongqing Medicine;2012-03
7 CAI Zhi-you1,YU Chang-yin2,YAN Yong1,ZHANG Jun2,HUANG Liang-guo2,YUAN Sheng-shan2,WANG Feng-ying2(1Department of Neurology,The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016;2Department of Neurology,The Affiliated Hospital of Zunyi Medical College,Zunyi 563003,China);Minocycline inhibits COX-2 and NF-κB expressions in rats of focal cerebral ischemia-reperfusion[J];Acta Academiae Medicinae Militaris Tertiae;2007-21
8 CAI Zhi-you1,YAN Yong1,YU Chang-yin2,ZHANG Jun2,HUANG Liang-guo2,HU Yong-tao2,ZHOU Ni2,WANG Feng-ying2 (1Department of Neurology,The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016; 2Department of Neurology,The Affiliated Hospital of Zunyi Medical College,Zunyi Guizhou 563003,China);Atorvastatin downregulates MMP-2,MMP-9 in brain of rats with focal cerebral ischemia-reperfusion[J];Acta Academiae Medicinae Militaris Tertiae;2008-19
9 Hu Xiaosong1,Song Haixing1,Liu jing1,Yang Zheng1,Li Xing2(1.Basic Medical Experimental Teaching Centre;2.Department of Human Anatomy,Chengdu Medical College,Chengdu,Sichuan 610083,China);Effect of cerebral ischemic preconditioning on expressions of TLR4 and GFAP around infarct area following focal ischemia in rat brains[J];Chongqing Medicine;2012-29
10 CUI Li-de,XU Xu-dong (Bisic Science School,Jining Medical University,Rizhao 276826,China);Modified of Suture in Rat in Middle Cerebral Artery Occlusion in the Model of Cerebral Ischemia[J];Journal of Jining Medical University;2009-05
China Proceedings of conference Full-text Database 1 Hits
1 Xiu-yuan ZHENG,Sheng-huo LI,Tie-bin YAN,Hui-hua LIU Department of Rehabilitation Medicine,Sun Yat-sen Memorial Hospital of Sun Yat-sen University,Guangzhou, 510120,China.;Effects Of Neural Electrical Stimulation On The Functional Recovery And The Expression Of Nestin Around The Acute Cerebral Infracted Area Of Rats[A];[C];2010
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 CHEN Ji quan, XIU Qing yu, SHEN Ce, YAN Ze minDepartment of Respiratory Medicine,Changzheng Hospital,The Second Military Medical University, Shanghai 200003,P.R.China;Treatment of Spontaneous Metastatic Lung Cancer with Interleukin-12 Gene-Modified Dendritic Cells Vaccine[J];Chinese Journal of Cancer;2002-12
2 YAN Li rong, ZHOU Hong tu, CHEN Ai juan, et al. (1.Department of Geriatrics; 2. Department of Hyperbaric Oxygen,the Affiliated Hospital of Jiangsu University, Zhenjiang 212001,China);The change of hyperbaric oxygen on serum MDA,SOD and NO of elderly patients with cerebral infarction[J];Chongqing Medical Journal;2004-03
3 LIU Lei,ZHAO Shi-fu,SONG Chuan,et al. (1.Department of Neurology,324 Hospital of PLA,Chongqing 400020,China; 2.Department of Neurology,Xingqiao Hosptial,the Third Military Medical University,Chongqing 400037,China);Inhibition of hyperbaric oxygen on iNOS expression of gerbil to alleviate ischemic nueronal apoptosis[J];Chongqing Medical Journal;2005-03
4 DING Peng 1,2, WANG Jia-Ning1, HUANG Yong-Zhang1, LUO Li-Na2, SHAO Fang21Institute of Clinical Medicine, People's Hospital, Yunyang Medical College, Shiyan 442000, China, 2General Hospital of Pingdingshan Coalmine Group, Pingdingshan 467000, China;Transduction of human Cu, Zn-superoxide dismutase mediated by an PEP-1 peptide into endothelial cells of human umbilical vein[J];Journal of the Fourth Military Medical University;2006-09
5 DENG Cong-Ying, ZHANG Li-Jun, LI Fei, CHENG Zhi, WU Nan, WANG Xian-Rong, FENG HuaDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing 400038, China;Preventive and therapeutic effects of hyperbaric oxygen and hypobaric hypoxia preconditioning on cerebral infarction after permanent middle cerebral artery occlusion in rabbits and its mechanism[J];Journal of the Fourth Military Medical University;2007-23
6 DONG Min1,2, XI Gang-Ming1, ZHANG Zheng-Hong1, WANG Jia-Ning31Department of Neurology, 3Institute of Clinical Medicine, Affiliated People's Hospital, Yunyang Medical College, Shiyan 442000, China, 2Hubei College of Traditional Chinese Medicine, Wuhan 43000, China;Transduction of PEP-1-SOD1 fusion protein into hippocampus in mice and its time course[J];Journal of the Fourth Military Medical University;2009-13
7 Qian Bu, Quan-Zhi Li Department of Ophthalmology, Traditional Chinese Medicine Hospital Affiliated to Sinkiang Medical University, Urumqi 830000, Sinkiang Uygur Autonomous Region, China;Experimental study of Interleunkin-2 of Tuiyi tablets on herpes simplex keratitis model in mice[J];International Journal of Ophthalmology;2008-09
8 KE Zunping1,2,WANG Jianing1,2,GUO Lingyun1,TANG Junming1,HUANG Yongzhang1,WANG Lei1,2,YANG Jianye11Institute of Clinical Medicine,Renmin Hospital of Yunyang Medical College,Shiyan 442000,China2 Renmin Hospital of Wuhan University,Wuhan 430060,China;Transduction of Human Cu,Zn-Superoxide Dismutase Mediated by PEP-1 Peptide into Isolated Rat Hearts with Ischemia Reperfusion Injury[J];Medical Journal of Wuhan University;2007-04
9 LI Ling-bo,LI Jing,LI Hong,et al(Deptment of Pharmacology,School of Basic Medicine,Jilin University,Changchun 130021,China);Protective effects of Gross Saponins of Tribulus Terrestris on experimental intracerebral hemorrhage in rats[J];Journal of Harbin Medical University;2006-02
10 XUE Yi-xue 1, ZANG Pei-zhuo 2, LIU Yun-hui 2, SHANG Xiu-li 1, AN Ping 1, YANG Zhi-hang 1,WANG Ping 1, WANG Yu-qin 1 (1.Department of Neurobiology; 2.Department of Neurosurgery, First Affiliated Hospital, China Medical University, Liaoning Shenyang 110001 China);Herpes Simplex Virus-mediated Interleukin-12 Gene Therapy for Malignant Brain Tumor of Rat[J];Progress of Anatomical Sciences;2004-02
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 Lin Lu1,2,Tao Guocai2,Yi Bin2(2.Department of Anesthesia,General Hospital,Chengdu Military Area Command,Sichuan 610083,China;2.Department of Anesthesia,Southwest Hospital,Third Military Medical University,Chongqing 400038,China);Difference of the characteristics of pain proceeding and the level of oxidative stress between the three neuropathic pain models[J];Chongqing Medicine;2011-01
2 Shi Dijian,Cheng Zepei(Department of Neurosurgery,Third People′s Hospital of Chongqing,Chongqing 400014,China);Effects of operation timing of minimally invasive surgery on superoxide dismutase and malondialdehyde in hematoma drainage of hypertensive intracerebral hemorrhage[J];Chongqing Medicine;2011-16
3 Chen Pan,Zhao Ming,Jiang Peng,Wang Shengjun,Gu Tengfei(Department of Anesthsiology,Affiliated Hospital of Jiangsu University,Zhenjiang,Jiangsu212000,China);Effects of dexmedetomidine on myocardial expression of Bax and Bcl-2 in rat myocardial ischemia/reperfusion injury[J];Chongqing Medicine;2012-16
4 LI He,ZHENG Shi-min(College of Veterinary Medicine,Northeast Agricultural University,Harbin 150030,China);The Research of TAT-SOD Protecting Nerve Cell from Apoptosis[J];China Animal Husbandry & Veterinary Medicine;2012-07
5 YANG Dan,LI Shi-de,WANG Yong-liang(Department of Orthopaedics,First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China);A Study of Pathophysiological Changes of Limb Ischemia-reperfusion Injury after Blocking Lower Abdominal Aorta in Rabbits[J];Guangxi Medical Journal;2010-06
6 WANG Jin-bao,WANG Shu-yuan,WANG Qi,TANG Long-xin(Department of Anesthesiology,Bethune International Peace Hospital of PLA,Shijiazhuang 050082,China);Effect of CD59 Protein Expression on Neuropathic Pain by Peripheral Nerve Injury[J];Clinical Misdiagnosis & Mistherapy;2011-12
7 LI Ling,et al.(The First People's Hospital of Yinchuan,Yinchuan 750001,China);IL-10,IL-18 expression around the hematoma after experimental intracerebral hemorrhage in rats[J];Ningxia Medical Journal;2009-11
8 HU Bo;ZHANG Xiang-hui;Kai-de minimally invasive surgery Hospital of Hunan;;Effect of Breviscapinun on oxidative stress of cerebral hemorrhage patients[J];For all Health;2013-17
9 Cai Zhiyou,Chen Ran,Wu Zhangsong.Department of Neurology,Liu′an People′s Hospital,the Liu′an Affiliated Hospital of Anhui Medical University,Anhui 237005,China;Retrospective Clinical Analysis of 48 Cases of Primary Brain Stem Hemorrhage with Activated Hyper-glycaemia[J];Journal of Medical Research;2010-12
10 LI Feng-Zeng,WANG Yong-Hong,CHEN Hui.Clinical Laboratories,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China;Predictive significance of the parameters of blood routine test on acute intracerebral hemorrhage patients in early time[J];Chinese Journal of Gerontology;2011-12
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 JIANG Qiang, LI Hua, LIU Wei, et al. (Department of Emergency,the 3rd People's Hospital, Chongqing 400014, China);The changes and significance of protein disulfide isomerase in rats with ischemic brain damage[J];Chongqing Medical Journal;2002-08
2 JIANG Li,CAI Fang cheng, ZHANG Xiao ping,et al.( Department of Neurology,Children′s Hospital, Chongqing University of Medical Sciences,Chongqing 400014,China);The role of hot shock reaction in protection of brain damage in premature brain after prolonged seizure[J];Chongqing Medical Journal;2003-04
3 DU Zhi-yong,YANG Tian-de,TAO Jun,et al.(Department of Anesthesiology, Xinqiao Hospital, the Third Military Medical University, Chongqing 400037,China);The effects of shengfu injection on myocardial enzymes CK,CK-MB of patients undergoing valve replacement[J];Chongqing Medical Journal;2004-11
4 LIU Lei, LIU Jing chang, XING Pei zhu, LIN Shi long (Second Department of Internal Medicine, The 324th Hospital of PLA, Chongqing 400000, China);Study on the mechanism of alleviating intercerebral edema in gerbils after cerebral ischemia by hyperbaric oxygen[J];Acta Academiae Medicine Militaris Tertiae;2001-01
5 LIU Lei, ZHAO Shi fu, LIN Chun mei,TANG Zheng cai (Department of Neurology, No. 324 Hospital of People Liberation Army of China, Chongqing 400020, China);Mechanism and rule of nitric oxide release from cerebral microvessel in gerbils with cerebral ischemia[J];Acta Academiae Medicine Militaris Tertiae;2002-09
6 YANG Liu-qing,LIU Xin,CAI Wei-hua,GE Feng-min,YAO Ye-xing (Department of Anesthesiology,Affiliated Hospital of Guangdong Medical College,Zhanjiang, 524001);Effect of Shenfu Injection on Apoptosis Following Acute Myocardial Ischemic Reperfusion in Rats[J];Academic Journal of Guangzhou Medical College;2005-02
7 WEI Wei,WEI Xin chuan,LI Yu,et al.(Department of Anesthesiology,West China Hospital,Sichuan University,Chengdu 610041,China);The Effects of Shengfu Injection on Circulatory Function in Cardiac Surgery[J];West China Medical Journal;2002-04
8 TIAN Shi-qiang, WANG Ren-zhi * , LI Gui-lin,et al. (Department of Neurosurgery, Peking Union Medical College Hospital,CAMS & PUMC, Beijing 100730,China);Modification of focal cerebral ischemia model in rats[J];Basic Medical Sciences and Clinics;2004-04
9 PAN Liang①,PAN Rong②,WANG Liang②,LIU Guo-Shu② (General Hospital of PLA,①Department of surgery,Intensive Care Unit;②Depar tment of Geriatric Cardiology,Beijing 100853 China);Protective Effects of Ginseng-Monkshood Extract on Rabbit’s Myocardium during Ischemia/Reperfusion[J];Pharmaceutical Journal of Chinese People's Liberation Army;2005-02
10 Cao Xia, Cao Bingzhen, Guo Shusu. The Jinan General Hospital of Jinan Command, Jinan 250031;CORRELATION BETWEEN TIME AND INFARCT VOLUME IN FOCAL CEREBRAL ISCHEMIA OF MIDDLE CEREBRAL ARTERY IN RATS[J];MEDICAL JOURNAL OF CHINESE PEOPLE'S LIBERATION ARMY;2000-02
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