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《Chongqing Medicine》 2009-15
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Expression and clinical significance of serum IGF-1 in patients with glioma

QIN Chuan1,LI Cheng-lu2,XIE Hui3,et al.(1.Department of Neurosurgery;3.Department of Radiology,People′s Hospital of Dazu County,Chongqing 402360,China;2.Department of Neurosurgery,Second People′s Hospital of Dazu County,Chongqing 402360,China;4.Department of Neurosurgery,First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China)  
Objective To investigate the relationship between IGF-1 and gliomas.Methods Sixty-seven cases with gliomas and 30 healthy persons were enrolled in this study.According to pathological diagnosis,all patients were divided into high-grade group and low-grade group.Healthy persons were control group.Serum IGF-1 level of all persons was measured and compared among three groups.Results Level of IGF-1 in high-grade group differed significantly from those in low-grade group and control group.Level of IGF-1 decreased significantly after tumorectomy.Conclusion The level of IGF-1 in the patients with glioma plays an important role in its pathologic types and prognosis.
【CateGory Index】: R739.4
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