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Research on treatment effects of Ginkgo Biloba Extract on chronic cerebral circulation insufficiency

QU Ying(Department of Neurology,Chongqing Emergency Medical Center,Chongqing 400014,China)  
Objective To approach on the clinical effects of the treatment of chronic cerebral circulation insufficiency(CCCI) with Ginkgo Biloba Extract(GBE).Methods One hundred and nine patients with cerebral circulation insufficiency were randomly divided into two groups in the neurologic department:therapy group(T group) and control group(N group).The therapy group was treatmented with GBE,the control group was treated with Xiangdan Injection.We observed the effects after 0,5,10 d therapy.Results The changes of Vs and hemodynamic parameters of vertebrobasilar were determined with transcranial Doppler.After 5 d GBE treatment and the cure rate,markedly effective rate of the T group were markedly better than those of the N group(P0.05),while there was statistical significance in hemorheology improvement(P0.05),such as blood viscosity,plasma viscosity,erythrocyte aggregation and hematocrit.After 10 d GBE treatment,the above parameters were significantly improved.The changes of LVA,RVA and BA of vertebrobasilar were also significantly improved(P0.05).Conclusion There are wide range of pharmacological effect of GBE,it can cover many aspects of pathophysiological links of CCCI.GBE has the functions of improving clinical symptoms,cerebral blood flow and hemodynamics of CCCI.
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