Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chongqing Medicine》 2012-22
Add to Favorite Get Latest Update

The evaluation on the positive predictive value of pancreatitis diagnosed by urine trypsinogen-2 in different groups

Diao Qizhi1,Mo Zhan1,Dong Linling2,Gao Zhongyan1,Li Yuan1(1.Department of Clinical Laboratory,Yongchuan Hospital,Chongqing Medical University,Yongchuan,Chongqing 402160,China;2.The Woman﹠Children Hospital of Yongchuan District,Yongchuan,Chongqing 402160,China)  
Objective To evaluate objectively the positive predictive value diagnosed pancreatitis of urine trypsinogen 2(TPS-2) in different groups,and avoid misdiagnosing pancreatitis only according to test result of urine TPS-2.Methods 136 cases clinic or hospital patients with positive result of urine TPS-2 were screened as research object.The amylase levels in blood and urine of the research object were detected,and pancreases of the research object were scanned by CT.The research object was diagnosed whether suffering pancreases or not according to diagnosis standard of pancreatitis.The research object was divided into different groups respectively according to abdominal pain symptoms,the measured value of amylase and primary diagnosed disease type.The positive likelihood ratio and positive predictive value of urine TPS-2 in these groups were calculated.Results The positive likelihood ratio and positive predictive value of urine TPS-2 in acute abdomen group were 1.10 and 52.38% respectively,whereas the positive likelihood ratio and positive predictive value in non acute abdomen group were 0.028 and 2.74% respectively.In the cancer group,the peptic ulcer group and the renal damage disease group,the positive likelihood ratio of urine TPS-2 were 0.03,0.00,0.02,and positive predictive value of urine TPS-2 were 2.00%,0.00%,2.94%,respectively.Conclusion There are significant difference in positive predictive value of urine trypsinogen 2 between different people group.We should consider prior probability of urine TPS-2 and other diagnosis markers of pancreatitis when pancreatitis is diagnosed according test result of urine TPS-2.
【Fund】: 重庆医科大学第五临床学院资助项目(2010017)
【CateGory Index】: R576
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved