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《Chongqing Medicine》 2014-05
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Effects of microsurgical technique treatment on acknowledge ability,activities of daily living, cortex blood perfusion and neuropeptide levels of brain glioma patients

Su Zulu;Chen Haohao;Su Hai;Zhang Yi;Department of Neurosurgery,the Affiliated Yongchuan Hospital of Chongqing Medical University;  
Objective To explore the effects of microsurgical technique treatment on acknowledge ability,activities of daily living,cortex blood perfusion and neuropeptide levels of brain glioma patients.Methods Microsurgical technique treatment and traditional operation were given to 87brain glioma patients,respectively.The acknowledge ability and activities of daily living were measured by HDS,MMSE and ADL;the cortex blood perfusion were revealed by PET,and the neuropeptide levels including arginine vasopressin,oxytocin,β-endorphin,somatostatin and neurotensin of patients from two different surgical groups were compared. Results As compared with the traditional operation,the acknowledge ability and activities of daily living of patients from microsurgical treatment group were significantly improved(P0.05),the cortex blood perfusion were statistically increased(P0.05)and the levels of five kinds of neuropeptide were all profoundly increased(P0.05).Conclusion Microsurgical technique treatment could improve the acknowledge ability and activities of daily living of brain glioma patients,the mechanisms of which could be the increase of cortex blood perfusion and theincrease of neuropeptide levels.
【Fund】: 重庆市永川区科委自然科学基金项目(ycstc 2013nc8083)
【CateGory Index】: R739.4
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